Liver Disease

News Liver Disease

• Albumin preserves kidney function and improves survival in abdominal infection of liver disease

  Treatment with albumin reduces renal impairment and mortality in cirrhotic patients with spontaneous bacterial peritonitis (SBP), one of the most common bacterial infections in this patient population, according to a new meta-analysis supported by CSL Behring and published in Clinical Gastroenterolo more

• Oxidative stress and altered gene expression occurs in a metabolic liver disease model

  A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency. This is the most common genetic liver disorder in children and can lead to ci more

• Selcia and Gilead Sciences Extend Liver Disease Drug Discovery Collaboration

  Selcia Limited announced a drug discovery collaboration agreement with Gilead Sciences, Inc.. Building on an established partnership following significant progress made to date, Selcia’s chemists and biologists will continue to provide integrated drug discovery services to support Gilead’s liver di more

Publications Liver Disease

• Understanding the Biological Context of NS5A–Host Interactions in HCV Infection: A Network-Based Approach

  Hepatitis C virus (HCV) is a major cause of chronic liver disease. HCV NS5A protein plays an important role in HCV infection through its interactions with other HCV proteins and host factors. In an attempt to further our understanding of the biological context of protein interactions between NS5A an more

• Effects of raftilose on serum biochemistry and liver morphology in rats fed with normal or high‐fat diet

  Non‐alcoholic fatty liver disease is the leading cause of chronic liver injury in developed countries. Oligofructose (OFS) is a prebiotic with proven benefits for health. The aim of the study is to evaluate the effect of 10% OFS on hepatic morphology and lipid metabolism in Wistar Kyoto rats submi more

• An updated review on drug‐induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

  Abstract Drug‐induced cholestasis is an important form of acquired liver disease and is associated with significant morbidity and mortality. Bile acids are key signaling molecules, but they can exert toxic responses when they accumulate in hepatocytes. This review focuses on the physiological me more

Market studies Liver Disease

• Fatty Liver Disease Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Fatty Liver Disease Global Clinical Trials Review, H1, 2012" provides data on the Fatty Liver Disease clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Fatty Liver Disease. It includes a more

• Non Alcoholic Fatty Liver Disease (NAFLD) – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Non Alcoholic Fatty Liver Disease (NAFLD) - Pipeline Review, H2 2012', provides an overview of the Non Alcoholic Fatty Liver Disease (NAFLD) therapeutic pipeline. This report provides information on the therapeutic development for Non Alcoholic Fatty Liver Di more

• Fatty Liver Disease – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Fatty Liver Disease - Pipeline Review, H2 2012', provides an overview of the Fatty Liver Disease therapeutic pipeline. This report provides information on the therapeutic development for Fatty Liver Disease, complete with latest updates, and special features more

Websites Liver Disease