Hydrophobic Interaction Chromatography

Companies Hydrophobic Interaction Chromatography

Pall GmbH, Germany

The life sciences industry is both driven and united by its need for speed to market, product reliability and economics. Pall’s leading edge filtration, separation and purification technologies and services play an essential and pivotal role in this industry’s ability to achieve these goals. In the more

Products Hydrophobic Interaction Chromatography

Sartobind® Phenyl for removal of hydrophobic contaminants

Process upgrades and increased flow rates in purification and polishing of therapeutic proteins: Sartorius Stedim Biotech is launching the first commercially available membrane adsorber for hydrophobic interaction chromatography (HIC) more

Customer-specific preparative HPLC Systems

LABOMATIC’s customer-specific solutions for preparative HPLC are based on our expertise in systems solutions with specific requirements more

News Hydrophobic Interaction Chromatography

• Scientists decipher the 3-D structure of the human genome

  Scientists have deciphered the three-dimensional structure of the human genome, paving the way for new insights into genomic function and expanding our understanding of how cellular DNA folds at scales that dwarf the double helix. In a paper in Science, they describe a new technology called Hi-C an more

White papers Hydrophobic Interaction Chromatography

• Increased productivity for downstream processing of biotherapeutics
  

  Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised upstream productivity in the production of recombinant proteins. Increased titres of up to 10 g/l stress the need for highly efficient and robust downstream processes (DSP). Most industrial bioprocess development groups apply generic DSP platforms that are designed to purify various candidates of the same class of proteins applying the same process design. Besides various filtration and virus inactivation steps, they usually involve two or three chromatographic unit operations with orthogonal separation modes. The use of high capacity chromatographic resins can help to overcome the DSP bottleneck by increasing process throughput and robustness more

• From Sephadex to GE Healthcare
  

  The success of chromatography as a technique for separating biomolecules is inevitably linked to the introduction of the gel filtration medium Sephadex(TM) by Pharmacia AB in 1959 more

Publications Hydrophobic Interaction Chromatography

• Bacteriocin activity against various pathogens produced by Pediococcus pentosaceus VJ13 isolated from Idly batter

  ABSTRACT Bacteriocins, an antimicrobial peptide, is known to have wide spectrum antimicrobial activity against various pathogens. Because they are easily digested in the intestine, they are considered as safe and are widely used as food preservatives. Hence their purification and characterizatio more

• CytoHiC: a cytoscape plugin for visual comparison of Hi-C networks

  Summary: With the introduction of the Hi-C method new and fundamental properties of the nuclear architecture are emerging. The ability to interpret data generated by this method, which aims to capture the physical proximity between and within chromosomes, is crucial for uncovering the three dimensi more

• High-throughput identification of long-range regulatory elements and their target promoters in the human genome

  Enhancer elements are essential for tissue-specific gene regulation during mammalian development. Although these regulatory elements are often distant from their target genes, they affect gene expression by recruiting transcription factors to specific promoter regions. Because of this long-range ac more

Websites Hydrophobic Interaction Chromatography