Herpes Simplex

News Herpes Simplex

• AiCuris: No Resistant Herpes Simplex Virus (HSV) Observed in Phase II Trial with Herpes Drug AIC316

  AiCuris announces that it will present the results of the resistance analysis from the recently completed phase II clinical trial with AIC316 at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in USA, Chicago. AIC316 is one of AiCuris lead compounds and was tested i more

• AiCuris’ Novel HSV Compound AIC316 Shows Efficacy in Phase II

  Phase II results for AiCuris' novel non-nucleosidic herpes simplex virus (HSV) inhibitor AIC316 reveal safety and efficacy in persons with genital herpes. The data were presented at the 19th ISSTDR Meeting (International Society for Sexually Transmitted Diseases Research) in Quebec, Canada, by the c more

• Cellectis’ Meganuclease Technology Used to Efficiently Prevent Viral Infection

  Cellectis  announced that scientists from Cellectis therapeutics, the French National Center For Medical Research (CNRS) and Institut de la Vision (Paris) have used its proprietary meganucleases to successfully prevent infection of cultured cells by a Herpes Simplex virus (HSV-1). The research has j more

Publications Herpes Simplex

• Effectiveness and safety of 0.15% ganciclovir in situ ophthalmic gel for herpes simplex keratitis – a multicenter, randomized, investigator-masked, parallel group study in Chin ...

  Lin T, Gong L, Sun XH, Zhao NQ, Chen W, Yuan HP, Shao Y, Gao MH, Tang H more

• Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein [Microbiology]

  Herpes simplex virus 1 (HSV-1) encodes an endoribonuclease that is responsible for the shutoff of host protein synthesis [virion host shutoff (VHS)-RNase]. The VHS-RNase released into cells during infection targets differentially four classes of mRNAs. Thus, (a) VHS-RNase degrades stable cellular mR more

• Viruses, Vol. 5, Pages 1208-1218: The Role of the CoREST/REST Repressor Complex in Herpes Simplex Virus 1 Productive Infection and in Latency

  REST is a key component of the HDAC1 or 2, CoREST, LSD1, REST (HCLR) repressor complex. The primary function of the HCLR complex is to silence neuronal genes in non-neuronal cells. HCLR plays a role in regulating the expression of viral genes in productive infections as a donor of LDS1 for expressio more

Market studies Herpes Simplex

• Herpes Simplex Infections – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Herpes Simplex Infections - Pipeline Review, H1 2012', provides an overview of the Herpes Simplex Infections therapeutic pipeline. This report provides information on the therapeutic development for Herpes Simplex Infections, complete with latest updates, and more

• Herpes Simplex Infections – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Herpes Simplex Infections - Pipeline Review, H2 2012', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Herpes Simplex Infections, complete with latest updates, and special feat more

• Herpes Market to 2018 - Genericization Compels Competitors Seeking Differentiation to Adopt Novel Drug Delivery Technologies

  GBI Research's report "Herpes Market to 2018 - Genericization Compels Competitors Seeking Differentiation to Adopt Novel Drug Delivery Technologies" finds that the global herpes market is an attractive one, and is expected to witness growth during the forecast period and to provide good opportunitie more

Websites Herpes Simplex