Genotyping

Products Genotyping

Gene expression analysis and genomic variation detection

Like all LightCycler® Instruments, the LightCycler® Nano produces high quality qPCR, genotyping and high resolution melting data using easy-fit reagents, reaction vessels and instrumentation more

News Genotyping

• Lab21 secures European and USA patents for HCV drug resistance genotyping

  Lab21 Limited has secured new patents in Europe and the USA relating to Hepatitis C (HCV) drug resistance as it continues to expand its intellectual property portfolio in infectious disease testing.   The patents cover technology allowing the genotypic identification of drug resistant mutations in t more

• LGC Genomics invests in new laboratory in Boston, US

  LGC Genomics announced the launch of its new US genomics services laboratory based at the Cumming’s centre in Beverly near Boston, Massachusetts. LGC Genomics has seen the number of employees in its US business expand from 1 to 20 in the past year and this new facility marks a significant step in it more

• Rutgers receives $10 million in support of national efforts to track genetic causes of alcoholism

  Rutgers University Cell and DNA Repository (RUCDR) has received a $10 million grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to provide DNA extraction, basic genetic testing, and repository services for more than 46,000 saliva samples, in support of national research effor more

White papers Genotyping

• LightCycler® 480 and 1536 Real-Time PCR Systems - Powerful Solutions for Different Throughput Levels
  

  During the past few years real-time PCR has been proven to be a key technology for gene expression analysis, for instance for gene expression profiling and array verification studies and for the genotyping of single nucleotide polymorphisms, both in industrial and public research, with major impact on the fields of drug discovery, molecular medicine and personalized health care more

• Application of the Amplifluor® SNPs Genotyping System using a FLUOstar OPTIMA microplate reader
  

  The detection of SNPs (single nucleotide polymorphisms) is an important tool for researchers in order to find mutations in DNA sequences. In this application note we describe a homogeneous fluorescence assay based on PCR. The Amplifluor® SNPs HT Genotyping System from Millipore was used to screen a number of samples with the help of the FLUOstar OPTIMA multidetection microplate reader from BMG LABTECH more

• Experimental Workflow for Fast and Accurate Genotyping of Scrapie-resistant/sensitive Sheep
  

  Several scientific studies support the claim that natural scrapie is associated with polymorphisms at three codons within the sheep prion protein (PrP) gene. Genotyping of these codons (codon 136 [alanine, valine], 154 [arginine, histidine], and 171 [glutamine, arginine, histidine]) might enable breeding of sheep flocks with high resistance to scrapie. Fast and reliable high-throughput genotyping of sheep is a major issue, since scrapie is a serious problem in several European countries. To address this, an experimental procedure for DNA preparation and PCR-based detection of codon 136, 154, and 171 polymorphisms was established. more

Publications Genotyping

• Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

  Visual refractive errors (REs) are complex genetic traits with a largely unknown etiology. To date, genome-wide association studies (GWASs) of moderate size have identified several novel risk markers for RE, measured here as mean spherical equivalent (MSE). We performed a GWAS using a total of 7280 more

• Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

  Associations between single nucleotide polymorphisms (SNPs) at 5p15 and multiple cancer types have been reported. We have previously shown evidence for a strong association between prostate cancer (PrCa) risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (TERT) gene that e more

• Fine mapping of the chicken congenital loco locus on chromosome 12

  Summary Congenital loco in chicks is characterized by an apparent lack of control of the muscles of the neck. This disorder is inherited as a simple Mendelian recessive disease, caused by an autosomal recessive gene, lo. To date, there are no reports on the localization of this gene. The objecti more

Market studies Genotyping

• Illumina, Inc. (ILMN) - Financial and Strategic SWOT Analysis Review

  Illumina, Inc. (ILMN) - Financial and Strategic SWOT Analysis Review Summary Illumina, Inc. (Illumina) is a molecular diagnostics company that principally focuses on the research and development of DNA and RNA Assays. It is involved in the development, manufacture and marketing of integrated syste more

• Applied DNA Sciences, Inc. (APDN) - Financial and Strategic SWOT Analysis Review

  Applied DNA Sciences, Inc. (APDN) is a biotechnology company, engaged in the commercialization of patented DNA security solutions to protect products, brands and intellectual property from counterfeiting and diversion. The company offers the ultimate DNA solutions designed to provide the highest lev more

• DR. Chip Biotech Inc. (4131) - Financial and Strategic SWOT Analysis Review

  Dr. Chip Biotechnology, Inc. (Dr. Chip) is a publicly traded biotechnology company, that is engaged in developing and manufacturing biochip products, image analysis devices and software, and biological reagents. It principally focuses on providing integrated solutions for medical diagnosis and resea more

Websites Genotyping