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Direct PCR-based identification of bacteraemia and fungaemia in antibiotic-treated patients

Using CE IVD SepsiTest™ highly enriched microbial DNA is provided to universal PCR analysis. This results in ultra-sensitive pathogen identification more

News Genes

  • Pulling the genomic puppetmaster's strings

    Duke researchers have developed a new method to precisely control when genes are turned on and active. The new technology allows researchers to turn on specific gene promoters and enhancers - pieces of the genome that control gene activity - by chemically manipulating proteins that package DNA. This more

  • Controlling genes with light

    Duke University researchers have devised a method to activate genes in any specific location or pattern in a lab dish with the flip of a light switch by crossing a bacterium’s viral defense system with a flower’s response to sunlight.With the ability to use light to activate genes in specific locati more

  • Scientists identify genetic clues for a big heart

    Bigger isn’t always better, even when it comes to the body’s most vital organs. An enlarged or thickened cardiac muscle can actually force the heart to work harder to pump blood throughout the body, weakening the organ until it eventually wears out. Despite the disastrous consequences of oversized o more

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  • Evolutionary Link Between Maternal Behavior and Eusociality Is Supported by Wasp Gene Expression

    A defining feature of eusociality is the presence of workers that abstain from reproduction and care for their siblings (i.e., workers forage for food and feed the brood). It has been proposed that this behavior evolved from maternal care behavior an more

  • Detection of Avian H5N1 Virus with the LightCycler® Instrument

    The avian H5N1 influenza virus has killed thousands of birds and caused several fatal cases in humans in Asia and Turkey. A fast and reliable test to identify the virus is urgently required for an effective epedemiological control, and associated medical research activities. RNA viruses mutate easily. Thus, detection has to focus on conserved sequence regions. The preferred gene for the detection of a broad spectrum of influenza A virus variants is the matrix protein (M2) gene. Tests for the specific detection of the H5N1 virus must detect its hemagglutinin (H5) and neuraminidase (N1) genes. more

  • RealTime ready RT-qPCR Assay Development and Qualification

    On the RealTime ready Configurator, we offer function tested human, mouse, and rat qPCR assays for gene expression quantification based on the unique Universal ProbeLibrary technology (UPL). The Universal ProbeLibrary is a set of short hydrolysis probes (8–9-mers) containing modified bases in order to stabilize the binding and thus ensure high flexibility together with good amplicon specificity more

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Definition

Pax genes

Pax genes Paired box (Pax) gene s are a family of tissue specific transcription factors containing a PAIRED domain and usually a partial or complete homeodomain. An octapeptide may also be present. Pax protein s are important in early animal de ... more

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