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Direct PCR-based identification of bacteraemia and fungaemia in antibiotic-treated patients

Using CE IVD SepsiTest™ highly enriched microbial DNA is provided to universal PCR analysis. This results in ultra-sensitive pathogen identification more

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  • Controlling genes with light

    Duke University researchers have devised a method to activate genes in any specific location or pattern in a lab dish with the flip of a light switch by crossing a bacterium’s viral defense system with a flower’s response to sunlight.With the ability to use light to activate genes in specific locati more

  • Scientists identify genetic clues for a big heart

    Bigger isn’t always better, even when it comes to the body’s most vital organs. An enlarged or thickened cardiac muscle can actually force the heart to work harder to pump blood throughout the body, weakening the organ until it eventually wears out. Despite the disastrous consequences of oversized o more

  • Researchers uncover key cancer-promoting gene

    One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth. Now, researchers at the University of Michigan Comprehensive Cancer Center have uncovered a key gene that may explain this paradox and provide a potential targe more

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  • Real-Time PCR Quantification of Plant miRNAs Using Universal ProbeLibrary Technology

    MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (18-25 nt in length) that are processed from larger hairpin precursors. Both plant and animal genomes encode miRNAs, and to date, there are over 4000 mature miRNA transcripts annotated. Although miRNAs represent a relatively abundant class of transcripts, their expression levels vary greatly among species and tissues. Less abundant miRNAs routinely fail detection using technologies such as cloning, northern hybridization and microarray analysis. Here, we present a real-time quantification method for accurate, sensitive, and economical detection of plant miRNAs based upon the stem-loop RT primer approach using an miRNA-specific primer coupled with a stem-loop specific Universal ProbeLibrary (UPL) probe. This approach represents a highly specific, sensitive, and easy-to-apply system to detect miRNAs. more

  • miRNA Extraction and Profiling on FFPE Samples

    RNA silencing is a mechanism of gene regulation whereby small double-stranded RNAs (dsRNAs) of 21-18 nucleotides in length cause mRNA degradation, mRNA translation, or chromatin modification. In the past years, more than 500 novel genes have been identified in animals and plants encoding small transcripts that can form small dsRNA hairpin structures. From these hairpin precursors, small 22-nt RNAs - so called microRNAs (miRNA) - are excised by dsRNA-specific endonucleases. The miRNAs are then integrated in ribonucleoprotein particles (RNPs). Most miRNAs in animals act by binding to partially complementary regions of the 3' untranslated region of their target mRNA, thereby blocking translation. more

  • Improved Performance of the LightCycler®

    Real-time reverse transcription-PCR (RT-PCR) is con­sidered the method of choice for any experiments requiring­ sensitive, specific, and reproducible quantification of mRNA molecules of interest. It is an essential tool for basic research, molecular medicine, and biotechnology. more

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GENEART - Your partner from gene synthesis to protein production!

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imaGenes - imaGenes

Email or User ID Password   register here Wednesday, 28 July 2010 FAQ   |  Contact   |  Your Account   |    Shopping Cart    Products Clones Clone Sets & Libraries FANTOM Clones & DNA Books Protein Arrays Synthetic Clones RNAi Services Next Generation Sequencing Microarray Services Clone-Identity Ve more

Roche NimbleGen | Home

    Products Technology Support Contact News Company   Sequence Capture Enrich thousands of targeted loci from complex genomic DNA with programmable Sequence Capture microarrays for sequencing on the GS FLX Sequencer from 454 Life Sciences.   CGH Measure DNA copy number differences between a test an more

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Definition

Pax genes

Pax genes Paired box (Pax) gene s are a family of tissue specific transcription factors containing a PAIRED domain and usually a partial or complete homeodomain. An octapeptide may also be present. Pax protein s are important in early animal de ... more

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