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Quality control of colorimetrically stained gels and blots
Comparison of 2 methods
In the pharmaceutical and food industry, using a scanner-based system is more recommended than using a camera-based system for the acquisition, documentation and analysis of colorimetrically stained gels, blots and TLC samples. The combination of a scanner with a suitable control and analysis software is decisively for completely meeting GxP guidelines...
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Nobel Prize for Solving the End-Replication Problem
The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic research and meticulous biochemical studies, they not only solved a fundamental problem in biology but also opened a new field of research and initiated the development of potential therapies against disease...
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HelpCorner - xCELLigence System
<p><strong>General</strong><br /> <br /> <strong>FAQ</strong>: How can I save time when using the xCELLigence System?<br /> <br /> <strong>HelpCorner</strong>: Automated monitoring and data collection contribute to significant time savings when using the xCELLigence System, with only a few...
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High-Throughput Cardiac Gene Expression Analysis Using the Universal ProbeLibrary and the Novel LightCycler® 1536 Real-Time PCR System
Although congenital heart malformations are the most common birth defects in humans, the underlying pathomechanisms remain widely unknown. Through linkage analyzes and candidate-gene approaches, several gene mutations causing congenital heart defects (e.g., CITED2, GATA4, NKX2-5) have been identified. However, most heart malformations display variable expressivity and penetrance, which indicates a multifactorial and multigenic basis. This suggests that the regulatory context of transcription factors plays an important role in the manifestation of the defects. In order to better understand the molecular pathways in cardiogenesis and disease we studied the global genetic network that is deregulated in malformed hearts...
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MagNA Pure 96 Cellular RNA Kits: RNA Isolation on the Fast Lane
Advancements in high-throughput gene expression analysis have set a new demand for automated isolation of cellular RNA from high sample numbers in parallel. The availability of the innovative MagNA Pure 96 System together with dedicated kits, protocols, and consumables sets a new standard in truly walkaway high-throughput automated nucleic acid sample preparation...
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