MolYsis-SNplus™ IVD

The MolYsis-SNplus IVD kit has been developed with the objective of providing laboratory professionals with a tool that facilitates the automated extraction of bacterial and fungal DNA from human samples, while simultaneously depleting the human DNA background. The presence of large amounts of human DNA can introduce "background noise" when using molecular techniques such as PCR or Next Generation Sequencing (NGS). The combination of human DNA depletion with contamination-free reagents and plastics maximizes the chances of detecting microbial DNA directly from human samples even at low levels, ensuring that even trace amounts can be captured and analysed. The method has been validated for a wide range of samples, including body fluids, swabs, and tissues.

Product Features:

• Fully automated process on the SelectNAplus device with flexible capacity of 1-12 samples per run
• Depletion of human DNA & isolation of bacterial and fungal DNA
• One process for body fluids, swabs & tissues
• All reagents are free of microbial DNA, no false-positive results from „kitome“

Applications:

Human DNA depletion is a powerful tool used for increasing the efficiency and accuracy of microbial DNA analysis in a wide variety of fields, from clinical diagnostics to quality control and research.

Diagnostic Added Value:

Detecting bacteria or fungi in human samples can be challenging, particularly when pathogens are present in minimal amounts. The removal of human DNA from samples greatly enhances the ability to detect these microorganisms, enabling the identification and analysis of even trace levels of microbial DNA. This method, in combination with ultrapure reagents, is critical for the accurate extraction of microbial DNA and plays a crucial role in the molecular-based diagnosis of infectious agents directly from patient samples.

_{MolYsis-SNplus IVD and SelectNAplus device are not for diagnostic use in the USA.}