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Elevated hormone flags liver problems in mice with methylmalonic acidemia

Study findings can immediately be applied to human patients with the disease


Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder. Based on this finding, medical teams treating patients with ...


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Your brain with a migraine


When migraine sufferers see the tell-tale squiggly lines, light flashes and blind spots of a migraine aura, they prepare for a migraine. When researchers see the brain image of an aura, they try to figure out what causes it and if there is a way to stop the start of the migraine. Now an ...


Early indicators of bone loss after hip replacement discovered


Hip replacements relieve pain and restore mobility for hundreds of thousands of patients in the United States each year, but about 40,000 of the more than 280,000 of these procedures performed annually in the U.S. are to replace failed previous hip replacements, at a direct cost of more than $1 ...


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Spikes of graphene can kill bacteria on implants


A tiny layer of graphene flakes becomes a deadly weapon and kills bacteria, stopping infections during procedures such as implant surgery. Operations for surgical implants, such as hip and knee replacements or dental implants, have increased in recent years. However, in such procedures, there is ...


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Mistakes in how proteins of the ear are built contribute to early hearing loss


From the moment a baby is born, they are put through a battery of screenings to test for all sorts of characteristics, which includes the sense of hearing. One in 500 newborns fail their newborn hearing screens and are diagnosed with hearing loss, making this the most prevalent sensory deficit in ...


Immune cells help rebuild damaged nerves


Immune cells are normally associated with fighting infection but in a new study, scientists have discovered how they also help the nervous system clear debris, clearing the way for nerve regeneration after injury. Researchers from Case Western Reserve University School of Medicine showed certain ...


Lifelike 3-D cinematic imaging promises numerous medical uses


Newly developed "cinematic rendering" technology can produce photorealistic 3D images from traditional CT and MRI data, with potential applications in medical education, communication with patients and physicians, and early disease detection. Recently introduced and not currently approved for ...


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Antibiotic-releasing polymer may help eradicate joint implant infection


A team of Massachusetts General Hospital (MGH) investigators has developed an antibiotic-releasing polymer that may greatly simplify the treatment of prosthetic joint infection. In their recent report the researchers describe how implants made from this material successfully eliminated two types ...


Patient gets ‘bionic eye’ vision system during retinal implant


More than two decades ago, doctors could do nothing for Walfre Lopez as his vision faded away due to a degenerative eye disease. Now, a revolutionary artificial-vision procedure done at University of Florida Health has given Lopez a new window to the world. Early this year, Lopez got what he ...


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New technique could increase success rate, life span of implantable devices


A new technique being developed at Purdue University could provide patients who require implantable catheters in the treatment of neurological and other disorders with a reliable and self-clearing catheter that could eliminate the need for additional surgery to replace failing ...


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