Receptors - 5 News from the science department by Uni Leipzig

Receptors - 5 News from the science department by Uni Leipzig

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New numbering system facilitates comparability of protein domains

Researchers analyse models using AI

30-Jan-2025 - Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies. Collaborative Research Centre (CRC) 1423 at Leipzig University aims to change this. Scientists at the Faculty of ...

receptors artificial intelligence G protein-coupled receptors
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Advance in pain relief research

Naturally occurring hederagenin binds to pain regulation receptor

13-Dec-2024 - A team of scientists led by Professor Annette Beck-Sickinger from the Institute of Biochemistry at Leipzig University has made an important advance in pain relief research. They discovered that hederagenin, a naturally occurring substance found in the medicinal plant ivy, binds to the pain ...

receptors chronic pain pain
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Biophysicists decipher functionality of adrenaline-binding receptor

In the future, researchers may be able to use these results to better avoid side effects when developing drugs

26-Jun-2024 - G protein-coupled receptors (GPCRs) are found throughout the human body and are involved in many complex signalling pathways. Despite their importance in many biological processes, the central mechanism of G protein-coupling and the associated signal transmission is not yet understood. A team of ...

receptors adrenaline drug design
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New regulator of eating behaviour identified

New potential approach to treating obesity

07-May-2024 - The rapidly escalating prevalence of overweight and obesity poses a significant medical challenge worldwide. In addition to people’s changing lifestyles, genetic factors also play a key role in the development of obesity. Scientists at Leipzig University and Heinrich Heine University Düsseldorf ...

receptors adipositas eating behaviour
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Controlling the metabolism of cancer cells

Researchers discover function of succinate receptor for cancer treatment

20-Dec-2021 - With their altered metabolism, cancer cells grow faster than normal cells. Scientists at Leipzig University’s Faculty of Medicine have now discovered that cancer cells need the succinate receptor to control their metabolic rate. This knowledge should in future help doctors to develop ...

receptors cancer cancer cells
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