Cells - 23 News by Universität Zürich
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Stress influences brain and psyche via immune system
This newly discovered connection could lead to new treatments for depression
12-Feb-2024 - Chronic stress affects the immune system and the brain. UZH researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress. In mice, it causes them to withdraw and avoid social contact. This newly discovered connection between body and mind in ...
Predictions of the effect of drugs on individual cells are now possible
The understanding of cell variation is pivotal for advancing more effective treatments
09-Oct-2023 - Experts from ETH Zurich, the University of Zurich, and the University Hospital Zurich have used machine learning to jointly create an innovative method. This new approach can predict how individual cells react to specific treatments, offering hope for more accurate diagnoses and ...
Commercial Dishwashers Destroy Protective Layer in Gut
Chemical residue on clean plates
02-Dec-2022 - Residue from rinse agents is left behind on dishes after they are cleaned in professional-grade dishwashers. This damages the natural protective layer in the gut and can contribute to the onset of chronic diseases, as demonstrated by researchers working with organoids at the Swiss Institute of ...
Immune System Reboot in MS Patients
Wiping out unwanted immune cells
14-Nov-2022 - Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards. A better understanding ...
Immunotherapy Reduces Lung and Liver Fibrosis in Mice
If this approach is also found to work in humans, it could lead to an effective treatment for fibrosis
19-Sep-2022 - Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring. Researchers at the University of Zurich have now developed an immunotherapy that specifically targets the cause – activated fibroblasts – while leaving normal connective tissue cells ...
Individual Cells Are Smarter Than Thought
25-Jul-2022 - Humans make decisions based on various sensory information which is integrated into a holistic percept by the brain. But how do single cells make decisions? Much more autonomously than previously thought, as researchers from the University of Zurich have now shown. Cells base their decisions not ...
Natural killer cells have surprising function
They manage wound healing in the skin
10-Sep-2021 - Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds. If the healing process is accelerated, the immune defense is weakened, researchers at the University of Zurich have now ...
Defective Epithelial Barriers Linked to Two Billion Chronic Diseases
Rise in allergic and autoimmune conditions
07-May-2021 - Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface of our skin, lungs and intestine. Defective epithelial barriers have been ...
Good immune defenses come with a risk of multiple sclerosis
How genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors
26-Oct-2020 - About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors. The ...
Genetic Malfunction of Brain Astrocytes Triggers Migraine
Cingulate cortex may represent a critical hub in the disease
25-Jun-2020 - Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence. Migraine is one of the most disabling disorders, ...
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