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Feverfew has been used for reducing fever, for treating headaches, arthritis and digestive problems. However, a review of the current studies have shown feverfew to be of no better use in the control of migraines than placebos; although it did note that there were very few studies into its effects.  It is hypothesised that by inhibiting the release of serotonin and prostaglandins, both of which are believed to aid the onset of migraines, feverfew limits the inflammation of blood vessels in the head. This would, in theory, stop the blood vessel spasm which is believed to contribute to headaches. The active ingredients in feverfew include parthenolide and tanetin. Capsules or tablets of feverfew generally contain at least 205 mcg, parthenolide; however, it might take four to six weeks before they become effective, and feverfew is not a remedy for acute migraine attacks. Parthenolide has also been found recently in 2005 to induce cell death in leukemia cancer stem cells. 
Recently, feverfew has been used by Aveeno skincare brand to calm red and irritated skin.
Feverfew is found around the world and in the U.S. particularly in western states such as California.
Adverse effects include: gastrointestinal distress, mouth ulcers, and antiplatelet actions.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Feverfew". A list of authors is available in Wikipedia.|