Diphenylamine as building blocker of Mannich bases

It is used as building blockers to form Mannich bases which are the most important pharmaceutical components as well as the products of industrial importance.Many research papers has been published regarding it to show the potentialities of it in building Mannich bases.

Diphenylamine

IUPAC name

Diphenylamine

Other names

N-Phenylbenzenamine;
N-Phenyl Aniline;
DPA;
Anilinobenzene;
(phenylamino)benzene;
N,N-diphenylamine;
big dipper;
C.I. 10355;
Phenylbenzenamine;
Diphenylamine;

Identifiers

CAS number

122-39-4

RTECS number

SMILES

c1ccccc1Nc2ccccc2

Properties

Molecular formula

C₁₂H₁₁N

Molar mass

169.23 g/mol

Appearance

White to yellow crystals

Density

1.2 g/cm³

Melting point

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53 °C (326 K)

Boiling point

302 °C (575 K)

Solubility in water

Slightly

Hazards

Main hazards

Toxic. Possible mutagen. Possible teratogen. Harmful in contact with skin, and if swallowed or inhaled. Irritant.

NFPA 704

R-phrases

R23 R24 R25 R33 R50 R53

S-phrases

S36 S37 S45 S60 S61

Flash point

152°C

Related Compounds

Related Amine

Aniline

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Diphenylamine is an aromatic amine with the structural formula (C₆H₅)₂NH. It has been used for scald control on apples in the United States, and it is a fungicide.

It has been used in a test for nitrates [1]

One synthesis is the reaction of aniline to form a mixture of ammonia and diphenyl amine.

It is considered to be and is known to be toxic and harmful to the environment.

It also finds use in DNA detection. See DNA extraction.

DNA Quantification Using Dimethylamine (click on PDF download link)