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Acid-citrate-dextrose



Acid Citrate Dextrose Solution (sometimes called Anticoagulant Citrate Dextrose Solution) is a solution of citric acid, sodium citrate and dextrose in water. It is mainly used as an anticoagulant to preserve blood, it is also used during procedures such as plasmapheresis instead of heparin. Two different solutions (Solution A and B) are defined by the United States Pharmacopeia.

Additional recommended knowledge

They have the following properties:

Solution A (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 20.59 to 22.75g
Dextrose (C6H12O6*H2O) 23.28g to 25.73g
Sodium (Na) 4.90g to 5.42g
Solution B (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 12.37 to 13.67g
Dextrose (C6H12O6*H2O) 13.96 to 15.44g
Sodium (Na) 2.94 to 3.25g

To make use:

AB
Citric Acid, anhydrous (C6H8O7) 7.3g 4.4
Sodium Citrate, dihydrate 22.0g 13.2
Dextrose, monohydrate (C6H12O6*H2O) 24.5g 14.7
Water for Injection to make 1000 mL1000 mL

Dissolve the ingredients and mix. Filter until clear.

References

United States Pharmacopeia 26, 2002, pp 158.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Acid-citrate-dextrose". A list of authors is available in Wikipedia.
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