Portrait Pharmacelsus is a preclinical CRO providing pharmacological, biological and bioanalytical test services in vitro and in vivo. Pharmacelsus offers to its customers services in the following areas: - Discovery Lead Optimization - in vivo pharmakokinetic and pharmacodynamic studies - disease-related bioassays in vivo and in vitro in the area of endocrinology and metabolic syndrome - in vitro toxicological studies covering multiple biological endpoints for cytotoxicity - multiplexing of different toxicological parameters from a single cell culture - detection of apoptosis and necrosis - cell cycle studies - determination of S-phase content - determination of immune status in rats and mice - bioanalytical services - Consulting in the preclinical field and early clinical phases