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211 Current white paper about the topic fluorescence

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Orphan Drugs – An Alternative to the declining Blockbuster Model?

20-01-2012

Up until the new millennium, the pharmaceutical industry grew stronger by 11%. However, the blockbuster model is increasingly at risk and the declining growth rates in the industry require a search for new strategies. In this context, orphan drugs are becoming increasingly important

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Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules

Thioflavin T aggregation assay to determine antibody stability using the FLUOstar Omega

03-11-2011

The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody candidates is measured in 96-well format

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Growth of Campylobacter using BMG LABTECH’s FLUOstar Omega equipped with ACU

Comparison of growth in a test tube incubator to 96 well plates in a FLUOstar Omega with ACU

03-11-2011

Growth of the fastidious microorganism Campylobacter jejuni was monitored using a FLUOstar Omega microplate reader equipped with the Atmospheric Control Unit (ACU) for independent control of oxygen and carbon dioxide. Growth was found tob e optimal at 7 % O2 and 10 % CO2

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DKSH Performance Materials: Introduction of new program to source products

Passing with flying colors

17-10-2011

Even under pressure to reduce costs, effective cooperation and hard work will always find a way to fulfill expectations. Most global players in the pharmaceutical industry are facing dramatic changes: blockbuster products launched in the 1990s will lose their patents over the next few years and ...

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Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications

14-10-2011

Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics

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GC-C-IRMS Determination of Hormones

eVol® Reduces Interference Caused by Solvents and Plastic Pipette Tips

26-09-2011

By amending methodology to utilize eVol® for sample preparation processes for GC-C-IRMS C isotope ratio analysis, the ISORA department has: improved sample preparation conditions and the GC-C-IRMS analysis results by removing the risk of ghost peaks, and increased their workflow, been able to ...

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CO2 Gas Calibration with eVol®, the digital analytical syringe

Quantification of CO2 Capture in Aqueous Solutions of Alcanolamine

26-09-2011

Using eVol® for injection of different volumes of CO2, CEP/TEP was able to achieve calibration of their instrument with levels of accuracy and precision not previously obtained using manual syringes. In addition, the needles on the eVol® syringes allow for sample collection directly from the gas ...

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Weighing Cytostatics in Safety Weighing Cabinets

14-07-2011

Weighing Cytostatics in Safety Weighing Cabinets: a contract manufacturer of medications for individual patients, was looking for a balance that he could also use under laminar-flow conditions, which prevail in safety workbenches, safety weighing cabinets and under laboratory fume hoods, for ...

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RealTime ready RT-qPCR Assay Development and Qualification

01-06-2011

On the RealTime ready Configurator, we offer function tested human, mouse, and rat qPCR assays for gene expression quantification based on the unique Universal ProbeLibrary technology (UPL). The Universal ProbeLibrary is a set of short hydrolysis probes (8–9-mers) containing modified bases in ...

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RealTime ready qPCR Assay Design and Configuration Portal Content

01-06-2011

The gene and transcript annotational content of the RealTime ready Configurator offers a combined view of three of the main gene annotation authorities. The positional information of the lab-tested RealTime ready assays regarding transcript or exon coverage is presented in a graphical overview ...

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