Haplobank – a biobank of reversible mutant embryonic stem cells
The Penninger lab at the IMBA developed a biobank of revertible, mutant embryonic stem cells. This cell bank – called Haplobank - contains over 100,000 mutated, conditional mouse embryonic stem cell lines, targeting about 70% of the protein-coding genome.
Genetic screens have revolutionized ... more
Only lethal if sugar is present
The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made the headlines a number of times over the years, including the spectacular “umbrella murder” in London in the 1970s, or more recently the ricin ... more
Tuberculosis: Researchers Uncover how Bacteria Burst our Cells
Scientists based in Vienna unveil the complex molecular structure that causes lethal infections by Mycobacterium tuberculosis (Mtb). Their findings might have implications for potential therapies against antibiotic-resistant tuberculosis.
An international team of scientists across Europe, i ... more