Systems Biology

News Systems Biology

• Merck Millipore Strengthens Bioscience Business by acquiring Amnis Corporation

  Merck Millipore announced it has agreed to acquire Seattle-based Amnis Corporation. Amnis designs, manufactures and markets high speed cell imaging instrumentation. The technology is used in flow cytometry applications in academic, biotech and pharmaceutical cell analysis and research. Amnis has 40 more

• Agilent Technologies Announces Winner of Third Annual Early Career Professor Award
  

  Agilent Technologies Inc. announced the winner of the company's third annual Agilent Early Career Professor Award. Dr. Michael Jewett, assistant professor of Chemical and Biological Engineering in the McCormick School of Engineering at Northwestern University, will receive the prize, which provides more

• Researchers shine light on how some melanoma tumors evade drug treatment

  Researchers shine light on how some melanoma tumors evade drug treatment Findings pinpoint a critical gene involved in melanoma growth, provide a framework for discovering ways to tackle cancer drug resistance The past year has brought to light both the promise and the frustration of developing new more

White papers Systems Biology

• qPCR Validation of Candidates for Modulators of the MAPkinase Signaling Pathway
  

  With the completion of the human genome sequence, the detailed understanding of gene functions by analyzing the structure, biological activities, and dynamics of the encoded proteins has become the next challenge. The technology of RNA interference (RNAi), which allows the silencing of genes by introduction of small interfering RNA (siRNA), is recognized as an extremely powerful tool for systematic high-throughput functional genomic screening. more

• High-Throughput and Complex Gene Expression Validation Using the Universal ProbeLibrary and the LightCycler® 480 System
  

  During the past decade, a considerable number of transcriptome profiling analyses have been reported. High-throughput approaches such as tagging-based serial analysis of gene expression (SAGE) and hybridization-based microarray technologies have been widely performed to profile gene expression [1]. However, these techniques are either laborious or costly, or may involve advanced technologies which limit the sampling depth, thus diminishing the sensitivity of analysis. Validation of gene expression profiles can be rapidly performed using an independent technique such as quantitative polymerase chain reaction (qPCR) to eliminate false results. In most laboratories, qPCR analysis has so far been performed on a small scale. more

Publications Systems Biology

• A multi-layer inference approach to reconstruct condition-specific genes and their regulation

  An important topic in systems biology is the reverse engineering of regulatory mechanisms through reconstruction of context-dependent gene networks. A major challenge is to identify the genes and the regulations specific to a condition or phenotype, given that regulatory processes are highly connec more

• Improving Functional Modules Discovery by Enriching Interaction Networks with Gene Profiles

  Abstract: Recent advances in proteomic and transcriptomic technologies resulted in the accumulation of vast amount of high-throughput data that span multiple biological processes and characteristics in different organisms. Much of the data come in the form of interaction networks and mRNA e more

• [Report] Structural Systems Biology Evaluation of Metabolic Thermotolerance in Escherichia coli

  As summer approaches, protein structures and network analysis pinpoint heat-sensitive metabolic nodes in a bacterium. more

Market studies Systems Biology

• Genomic Sequencing Technologies for Medicine: Market Prospects 2011-2021

  How will the genomic sequencing market develop this decade? Our new report shows you that industry and market's revenue potential from 2011 to 2021, discussing its prospects. This report covers technology to support genomics, with an emphasis on pharma R&D. We aim to save you time and aid your deci more

Websites Systems Biology