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Saccharomyces Cerevisiae

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  • Methylation of the Arginine 2 in Histone H3 Controls Deposition of Lysine 4 Tri-Methylation

    In a recent study, Kirmizis et al. demonstrated that H3R2 is methylated not only in mammals but also in Saccharomyces cerevisiae. By using a specific H3R2me2a antibody in a ChIP-on-Chip analysis the authors determined the distribution of the methylation throughout the yeast genome, finding an enrichment of H3R2me2a at all heterochromatic genes, at inactive euchromatic genes, and at the 3´-end of moderately transcribed genes. The presence of H3R2 methylation inversely correlates with the presence of H3K4 tri-methylation (H3K4me3) in all cases, reflecting the fact that H3R2 methylation disrupts the ability of the Set1-complex to methyl­ate H3K4 by preventing the Set1-methyltransferase subunit Spp1 from binding to to histone H3. These results show that H3R2 methylation controls the distribution of H3K4me3 and provide the first mechanistic insight into the function of arginine methylation on chromatin. more

  • Genome Sequencer 20 System: Breakthrough in a New Applications Age of Sequencing

    The Genome Sequencer 20 System is an ultra-high-throughput automated DNA sequencing system capable of carrying out and monitoring sequencing reactions in a massively parallel fashion. Since the Genome Sequencer 20 System provides a complete solution for ultra-high-throughput DNA sequencing, an individual researcher can for the first time prepare samples and sequencing reactions, generate sequence reads, and assemble genome sequence data within days. more

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BAC BV – The Affinity Experts

Welcome to BAC BAC is an established biotech company providing the life science industry with unparalleled protein purification technologies for drug manufacture and research. These CaptureSelect ® products possess a combination of unique properties such as stability, affinity and selectivity, which more

Chemical Pathway Analysis Software and Database from Ingenuity

Home Products & Services Research and Analysis Solutions > IPA > Ingenuity Answers > Ingenuity    Analysis Services Informatics Solutions Enterprise Solutions eCommerce Solutions Training Search Publications Library News & Events Partners About Us Careers Additional Information For additional inform more

BAC BV – The Affinity Experts

BAC Affinity Ligand Licensed for Clinical and Commercial Scale-up of LFB Biotechnologies’ Recombinant Factor VIIa Naarden, The Netherlands , 13 April 2010 – BAC BV, the leading provider of antibody based affinity purification technology, has announced that it has extended its license agreement with more

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Definition

Saccharomyces cerevisiae

Saccharomyces cerevisiae Saccharomyces cerevisiae is a species of budding yeast . It is perhaps the most useful yeast owing to its use since ancient times in baking and brewing . It is believed that it was originally isolated from the skin ... more

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