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RNA Interference

The technique regularly makes the science headlines, and drugs it is based on have reached the clinical development stage – RNA interference is on everyone’s lips, thanks to enabling a comparatively straightforward technique of silencing genes. The market volume of RNAi products and services is predicted to reach four thousand million US dollars by 2017, with siRNA synthesis seen as having the greatest growth potential.

Companies RNA Interference

Merck Chemicals GmbH, Germany

Merck Millipore is the Life Science division of Merck KGaA of Germany and offers a broad range of innovative, performance products, services and business relationships that enable our customers’ success in research, development and production of biotech and pharmaceutical drug therapies. Through ded more

SIRION BIOTECH GmbH, Germany

SIRION Biotech is Europe's leading commercial supplier of viral vectors used for genetic cell modelling, gene target validation and gene therapy- and vaccination studies. Since its foundation in 2007, SIRION’s mission has been to change the paradigm for viral vector supplies. It has the ability to more

Products RNA Interference

Speed up compound & target research with novel and reliable in vitro cell models

RNAiONE - Identification of optimal shRNA sequences for knockdown cell systems, for target validation and for screening applications more

News RNA Interference

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White papers RNA Interference

  • qPCR Validation of Candidates for Modulators of the MAPkinase Signaling Pathway

    With the completion of the human genome sequence, the detailed understanding of gene functions by analyzing the structure, biological activities, and dynamics of the encoded proteins has become the next challenge. The technology of RNA interference (RNAi), which allows the silencing of genes by introduction of small interfering RNA (siRNA), is recognized as an extremely powerful tool for systematic high-throughput functional genomic screening. more

  • Dynamics of Kinases Involved in Cell Growth Using the xCELLigence System

    Studies investigating endogenous cellular regulatory mechanisms have substantially pushed the application of high-throughput screens. RNA interference has developed into an extremely powerful tool for mediating the loss-of-function of specific mRNA molecules and preventing their translation into proteins. Numerous studies have helped to uncover novel gene functions in many biological processes, but most have used single endpoint analysis as readout for the respective phenotypes to characterize the outcome of a cascade of regulatory mechanisms. The xCELLigence System offers a new way to analyze the effect of gene knock downs on living cells, as the system provides continuous, quantitative information about the electrical impedance at the bottom surface of microtiter plates. Thus, any change in cell number, cell morphology or cell attachment can be detected in real-time. more

  • HelpCorner - Gene Silencing

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Publications RNA Interference

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Market studies RNA Interference

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Websites RNA Interference

Alnylam Pharmaceuticals Home

Home     About Alnylam     Leadership in RNAi     Programs & Pipeline     Intellectual Property     Business Development     Events & Media Library     Investors Legal     Site Map   Copyright © 2008 Alnylam Pharmaceuticals, Inc. All Rights Reserved more

Cenix BioScience GmbH: The HT-RNAi Specialist

Company Info Science & Technology Research Services News & Archive Careers Contact Info   Oct 26, 2009 Cenix BioScience celebrates 10th anniversary   Jun 15, 2009 Cenix BioScience expands relationship with AstraZeneca, signing multi-project research agreement   ... Mar 19, 2009 Cenix BioScience foll more

imaGenes - imaGenes

Email or User ID Password   register here Wednesday, 28 July 2010 FAQ   |  Contact   |  Your Account   |    Shopping Cart    Products Clones Clone Sets & Libraries FANTOM Clones & DNA Books Protein Arrays Synthetic Clones RNAi Services Next Generation Sequencing Microarray Services Clone-Identity Ve more

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Definition

RNA interference

RNA interference trims double stranded RNA, to form small interfering RNA or microRNA . These processed RNAs are incorporated into the RNA-induced silencing complex (RISC), which targets messenger RNA to prevent translation . RNA interferen ... more

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