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RNA Interference

The technique regularly makes the science headlines, and drugs it is based on have reached the clinical development stage – RNA interference is on everyone’s lips, thanks to enabling a comparatively straightforward technique of silencing genes. The market volume of RNAi products and services is predicted to reach four thousand million US dollars by 2017, with siRNA synthesis seen as having the greatest growth potential.

Companies RNA Interference

SIRION BIOTECH GmbH, Germany

SIRION Biotech is Europe's leading commercial supplier of viral vectors used for genetic cell modelling, gene target validation and gene therapy- and vaccination studies. Since its foundation in 2007, SIRION’s mission has been to change the paradigm for viral vector supplies. It has the ability to more

Products RNA Interference

Speed up compound & target research with novel and reliable in vitro cell models

RNAiONE - Identification of optimal shRNA sequences for knockdown cell systems, for target validation and for screening applications more

News RNA Interference

  • Lipid nanoparticles for gene therapy

    Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Until now, viral systems have been the most effective method for delivering genetic matter but they pose significant safety problems. "Non-viral vectors, including SLNs and NLCs more

  • CSIRO maintains foundational patent for RNAi gene silencing technology after European opposition

    The Commonwealth Scientific and Industrial Research Organisation (CSIRO), has successfully defended its foundational patent in Europe for RNA interference (RNAi) gene silencing technology. RNAi technology is a powerful method that is widely used as a research tool to test the function of genes and i more

  • How a molecular Superman protects the genome from damage

    How many times have we seen Superman swoop down from the heavens and rescue a would-be victim from a rapidly oncoming train? It's a familiar scenario, played out hundreds of times in the movies. But the dramatic scene is reenacted in real life every time a cell divides. In order for division to occu more

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White papers RNA Interference

Definition

RNA interference

RNA interference trims double stranded RNA, to form small interfering RNA or microRNA . These processed RNAs are incorporated into the RNA-induced silencing complex (RISC), which targets messenger RNA to prevent translation . RNA interferen ... more

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