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RNA Interference

The technique regularly makes the science headlines, and drugs it is based on have reached the clinical development stage – RNA interference is on everyone’s lips, thanks to enabling a comparatively straightforward technique of silencing genes. The market volume of RNAi products and services is predicted to reach four thousand million US dollars by 2017, with siRNA synthesis seen as having the greatest growth potential.

Companies RNA Interference

SIRION BIOTECH GmbH, Germany

SIRION BIOTECH is a technology leader in the field of functional gene analysis and cell models for basic research, drug and compound development. The company serves leading European and Japanese Drug and Biotech companies as a provider of latest technologies for them to advance identification of nov more

Merck Chemicals GmbH, Germany

Merck Millipore is the Life Science division of Merck KGaA of Germany and offers a broad range of innovative, performance products, services and business relationships that enable our customers’ success in research, development and production of biotech and pharmaceutical drug therapies. Through ded more

Products RNA Interference

Speed up compound & target research with novel and reliable in vitro cell models

RNAiONE - Identification of optimal shRNA sequences for knockdown cell systems, for target validation and for screening applications more

News RNA Interference

  • Scientists discover new, noncommittal mechanism of drug resistance

    Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs. These permanent mutations were once thought to be the only way for drug-resistant strains to evolve. Now a new study has shown that microorganisms can use a tem more

  • PBL awared further US patents on short RNAi molecules

    Plant Bioscience Limited (PBL) announced that the United States Patent and Trademark Office (USPTO) has issued US Patent No. 8,759,102 and US Patent No. 8,779,236 with fundamental claims directed to RNAi in cells and organisms to effect gene silencing. These two new patents granted add to the streng more

  • Biochemist developed way to silence genes that cause diseases

    Thanks to the ground-breaking research of 47-year-old German biochemist Thomas Tuschl, silencing genes is no longer a utopia. His method of switching off human genes is the basis for promising therapies to treat genetic disorders that trigger serious conditions such as haemophilia, amyloidosis, andp more

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White papers RNA Interference

  • High-Throughput Cardiac Gene Expression Analysis Using the Universal ProbeLibrary and the Novel LightCycler® 1536 Real-Time PCR System

    Although congenital heart malformations are the most common birth defects in humans, the underlying patho­mechanisms remain widely unknown. Through linkage analyzes and candidate-gene approaches, several gene mutations causing congenital heart defects (e.g., CITED2, GATA4, NKX2-5) have been identified. However, most heart malformations display variable expressivity and pene­trance, which indicates a multifactorial and multigenic basis. This suggests that the regulatory context of transcription factors plays an important role in the manifestation of the defects. In order to better understand the molecular pathways in cardiogenesis and disease we studied the global genetic network that is deregulated in malformed hearts more

  • qPCR Validation of Candidates for Modulators of the MAPkinase Signaling Pathway

    With the completion of the human genome sequence, the detailed understanding of gene functions by analyzing the structure, biological activities, and dynamics of the encoded proteins has become the next challenge. The technology of RNA interference (RNAi), which allows the silencing of genes by introduction of small interfering RNA (siRNA), is recognized as an extremely powerful tool for systematic high-throughput functional genomic screening. more

  • HelpCorner - Gene Silencing

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Publications RNA Interference

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Market studies RNA Interference

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Websites RNA Interference

Alnylam Pharmaceuticals Home

Home     About Alnylam     Leadership in RNAi     Programs & Pipeline     Intellectual Property     Business Development     Events & Media Library     Investors Legal     Site Map   Copyright © 2008 Alnylam Pharmaceuticals, Inc. All Rights Reserved more

Cenix BioScience GmbH: The HT-RNAi Specialist

Company Info Science & Technology Research Services News & Archive Careers Contact Info   Oct 26, 2009 Cenix BioScience celebrates 10th anniversary   Jun 15, 2009 Cenix BioScience expands relationship with AstraZeneca, signing multi-project research agreement   ... Mar 19, 2009 Cenix BioScience foll more

imaGenes - imaGenes

Email or User ID Password   register here Wednesday, 28 July 2010 FAQ   |  Contact   |  Your Account   |    Shopping Cart    Products Clones Clone Sets & Libraries FANTOM Clones & DNA Books Protein Arrays Synthetic Clones RNAi Services Next Generation Sequencing Microarray Services Clone-Identity Ve more

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Definition

RNA interference

RNA interference trims double stranded RNA, to form small interfering RNA or microRNA . These processed RNAs are incorporated into the RNA-induced silencing complex (RISC), which targets messenger RNA to prevent translation . RNA interferen ... more

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