Protein maintains order in the nucleus
Two metres of DNA are packed into the cell nucleus, presumably based on a strictly defined arrangement. Researchers working with biologist Patrick Heun from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have now succeeded in explaining a phenomenon, which was first o ... more
Making and breaking heterochromatin
To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. Scientists of the Max Planck Institute of Immunobiology ... more
Dosage compensation in male flies: Balance between sexes
The sex of many organisms is determined by the number of X chromosomes. In humans, for example, women have two X chromosomes, whereas men have only one X chromosome, but also have an additional Y chromosome. The same is true of other mammals, and of fruit flies, as well. Why this does not r ... more