Pharmacogenetics

News Pharmacogenetics

• Quintiles, London Genetics ally to enhance drug discovery and development through pharmacogenetics

  Quintiles and London Genetics announced a strategic alliance to offer the biopharmaceutical industry pharmacogenetics solutions to advance personalized medicine. Financial terms were not disclosed. Under the non-exclusive alliance, Quintiles and London Genetics will collaborate to help biopharma co more

• Trophos initiates pivotal efficacy study of olesoxime in Spinal Muscular Atrophy

  Trophos SA announced the initiation of the pivotal efficacy study of olesoxime in the rare, neurodegenerative condition, Spinal Muscular Atrophy (SMA). The study is substantially funded by Trophos’ partnership with the Association Française contre les Myopathies (AFM). The trial protocol has benefit more

• London Genetics expands its senior advisory team

  London Genetics Limited announced that it has augmented the strength of its team with the appointment of two senior advisers, Professors Stephen DeCherney and Munir Pirmohamed. Stephen DeCherney MD, MPH, is Professor of Medicine at the University of Carolina, and was previously President, Global Cl more

White papers Pharmacogenetics

• LightCycler® 480 Instrument: High-throughput Genotyping for TLR-8 SNPs
  

  Determining frequencies of single nucleotide polymorphisms (SNPs) in large populations is of great interest in different fields of molecular medicine, including pharmacogenetics, risk profiling, and candidate gene testing. Several SNPs within innate immunity genes have been shown to play a role in complex human diseases. Among them, SNPs within Toll-like Receptor (TLR) genes are known to influence susceptibility to infectious diseases. more

Publications Pharmacogenetics

• Personalized medicine in oncology: where have we come from and where are we going?

  Current advances in the biology of cancer and emergence of new tools for genome analysis have opened clinical perspectives in oncology, generally termed as ‘personalized medicine’. This broad term must encompass previous well-proven strategies, such as pharmacogenetics- and pharmacokinetics-based do more

• Clinical relevance of pharmacogenetics in gastrointestinal stromal tumor treatment in the era of personalized therapy

  Gastrointestinal stromal tumor (GIST) is a well-recognized and now relatively well-understood mesenchymal tumor. Before the imatinib era, the treatment of metastatic GIST was frustrating owing to its refractoriness to conventional chemotherapy and radiotherapy. After a metastatic GIST patient was gr more

• An Intronic Variant in OPRD1 Predicts Treatment Outcome for Opioid Dependence in African-Americans

  An Intronic Variant in OPRD1 Predicts Treatment Outcome for Opioid Dependence in African-Americans Neuropsychopharmacology advance online publication, May 15 2013. doi:10.1038/npp.2013.99 Authors: Richard C Crist, Toni-Kim Clarke, Alfonso Ang, Lisa M Ambrose-Lanci, Falk W Lohoff, And more

Market studies Pharmacogenetics

• AutoGenomics and PGXL Laboratories to Partner to Expand Molecular Testing in Pharmacogenetics - Deal Analysis from GlobalData

  Introduction GlobalData’s medical equipment report, “AutoGenomics and PGXL Laboratories to Partner to Expand Molecular Testing in Pharmacogenetics” provides key insights on the deal. The report provides analysis and impact on the global in-vitro diagnostics market as a result of the deal. This repo more

Websites Pharmacogenetics