Pain

News Pain

• PRAC recommends restricting the use of flupirtine-containing medicines

  The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded its review of flupirtine-containing medicines and recommended restrictions in their use. The Committee recommended that oral flupirtine medicines and suppositories should only be used to treat acute (short-term) pain in adult more

• PRAC recommends restricting the use of codeine when used for pain relief in children

  The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended a series of measures to address safety concerns with codeine-containing medicines when used for the management of pain in children. This follows the PRAC’s review of reports of children who developed s more

• PRAC recommends the same cardiovascular precautions for diclofenac as for selective COX-2 inhibitors

  The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that the effects of the painkiller diclofenac on the heart and circulation when given systemically (by means such as capsules, tablets or injections) are similar to those of selective COX-2 inhibitors, a more

Publications Pain

• Vigilance for pain-related faces in a primary task paradigm: an ERP study

  Lautenbacher S, Dittmar O, Baum C, Schneider R, Keogh E, Kunz M more

• Health related quality of life in patients recently diagnosed with multiple sclerosis

  Objective To describe a representative population of patients recently diagnosed with MS in terms of both motor and non‐motor disability. In particular we wanted to examine the HRQoL in this population to get a better understanding of what impact various clinical features have on the patients' e more

• Histamine Modulation of Acute Nociception Involves Regulation of Nav1.8 in Primary Afferent Neurons in Mice

  Summary Aims To explore the role of histamine in acute pain perception and its possible mechanisms. Methods Pain‐like behaviors induced by four types of noxious stimuli (hot‐plate, tail‐pressure, acetic acid, and formalin) were accessed in mice. Nav1.8 expression and functions in primar more

Market studies Pain

• Dental Pain Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Dental Pain Global Clinical Trials Review, H1, 2012" provides data on the Dental Pain clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Dental Pain. It includes an overview of the trial n more

• Acute Pain – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Acute Pain - Pipeline Review, H1 2012', provides an overview of the Acute Pain therapeutic pipeline. This report provides information on the therapeutic development for Acute Pain, complete with latest updates, and special features on late-stage and discontin more

• Musculoskeletal Pain Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Musculoskeletal Pain Global Clinical Trials Review, H1, 2012" provides data on the Musculoskeletal Pain clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Musculoskeletal Pain. It includes more

Websites Pain