Infectious Diseases

News Infectious Diseases

• Protein improves efficacy of tumor-killing enzyme

  Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio®, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells. By attac more

• Use of antibiotics in animals

  The European Medicines Agency (EMA) will provide advice on the impact on public health and animal health of the use of antibiotics in animals. The request was made by the European Commission as part of its ‘Action Plan against the rising threats from Antimicrobial Resistance (AMR)’. Antibiotics are more

• Study suggests link between untreated depression and response to shingles vaccine

  Results from a new study published in Clinical Infectious Diseases suggest a link between untreated depression in older adults and decreased effectiveness of the herpes zoster, or shingles, vaccine. Older adults are known to be at risk for shingles, a painful condition caused by the reactivation of more

White papers Infectious Diseases

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

• LightCycler® 480 Instrument: High-throughput Genotyping for TLR-8 SNPs
  

  Determining frequencies of single nucleotide polymorphisms (SNPs) in large populations is of great interest in different fields of molecular medicine, including pharmacogenetics, risk profiling, and candidate gene testing. Several SNPs within innate immunity genes have been shown to play a role in complex human diseases. Among them, SNPs within Toll-like Receptor (TLR) genes are known to influence susceptibility to infectious diseases. more

• Characterizing Environments: Recent Discoveries Enabled by Metagenomic Analysis with the Genome Sequencer FLX System

  Metagenomics is the study of genomic content in a complex mixture of microorganisms. The two primary goals of this approach are to characterize the organisms present in a sample and identify what roles each organism has within a specific environment. Metagenomics samples are found nearly everywhere, including several microenvironments within the human body, soil samples, extreme environments such as deep mines, and the various layers within the ocean. Until recently, technical and economic constraints limited the depth of analysis necessary to obtain a representative picture of microbial and viral communities, their metabolic profiles, and their adaptation dynamics. Advancements in sequencing technologies, including the introduction of massively parallel pyrosequencing with the Genome Sequencer FLX System, have enabled a tremendous groundswell of research in the field of metagenomics. Dramatic improvements in throughput and the elimination of biased cloning steps have extended the field far beyond tradition more

Publications Infectious Diseases

• A crowded calendar

  Nature Reviews Microbiology 11, 357 (2013). doi:10.1038/nrmicro3045 The preponderance of global public health campaigns reflects the ongoing importance of the need to raise awareness of infectious diseases, and their devastating effects. more

• [News & Analysis] Infectious Diseases: Amid Heightened Concerns, New Name for Novel Coronavirus Emerges

  Pathogen to be christened Middle East respiratory syndrome coronavirus, or MERS-CoV. more

• PHISTO: pathogen–host interaction search tool

  Summary: Knowledge of pathogen–host protein interactions is required to better understand infection mechanisms. The pathogen–host interaction search tool (PHISTO) is a web-accessible platform that provides relevant information about pathogen–host interactions (PHIs). It enables access to the most u more

Market studies Infectious Diseases

• Uganda Pharmaceuticals and Healthcare Report Q2 2012

  BMI View: Uganda's pharmaceutical market is typical of developing markets: defined by an absence of a clear regulatory framework, a dependence upon drug imports and low healthcare expenditure per capita. Economic growth will aid the development of Uganda's pharmaceutical and healthcare sectors as af more

• HIV-AIDS Testing Markets

  There are an estimated 33.3 million people living with HIV (the virus which causes AIDS) worldwide and approximately 2.6 million people are newly-infected each year. While the Asian and African regions account for more than 90% of the HIV-infected population (with the highest number in Sub-Saharan A more

• BIOQUAL, Inc. - Strategic SWOT Analysis Review

  BIOQUAL, Inc. (Bioqual) is a public traded, research, development and consulting company and is engaged in providing quality research, development and consulting services to Government and commercial contract clients. The company is accredited by the association for the assessment and accreditation more

Websites Infectious Diseases