Topic hypertension

News hypertension

• Actelion's macitentan meets primary endpoint in pivotal Phase III study

  Actelion announced that initial analysis indicates that the pivotal, long-term, event-driven study SERAPHIN with macitentan, a novel dual endothelin receptor antagonist, in 742 patients suffering from pulmonary arterial hypertension (PAH) and treated for up to three and a half years, has met its pri more

• Hypertension, a widespread disease - less salt helps

  What would the soup be like without salt? The addition of salt in the processing of food has multiple benefits: salt can extend the shelf life of foods and improve their taste, and it is involved in numerous basic metabolic processes in our body. But too much of a good thing can have detrimental hea more

• Takeda’s Edarbi receives European marketing authorisation for the treatment of essential hypertension

  Takeda Pharmaceutical Company Limited announced that the European Commission has granted marketing authorisation for Edarbi® (azilsartan medoxomil), a new once-daily angiotensin receptor blocker (ARB) (also known as angiotensin II receptor antagonist [AIIRA]) for the treatment of essential hypertens more

Publications hypertension

• Atrial natriuretic peptides in Han Wistar, Sprague–Dawley and spontaneously Hypertensive rats

  ABSTRACT The atrial natriuretic peptide (ANP) and its precursor (N‐terminal fragment of atrial natriuretic peptide, NT‐proANP) are natriuretic peptides released into the circulation as a consequence of an acute atrial stretch. As for the brain natriuretic peptide and its N‐terminal fragment, the more

• BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGF{beta}-TAK1-MAPK pathways in PAH

  Pulmonary arterial hypertension (PAH) is a cardiovascular disorder associated with enhanced proliferation and suppressed apoptosis of pulmonary arterial smooth muscle cells (PASMCs). Heterozygous mutations in the type II receptor for bone morphogenetic protein (BMPR2) underlie the majority of the i more

• Furosemide‐induced genotoxicity and cytotoxicity in the hepatocytes, but weak genotoxicity in the bone marrow cells of mice

  Abstract Furosemide (FS) is a potent loop diuretic widely used in the management of fluid retention associated with cardiac, renal, and hepatic failure as well as for the treatment of hypertension. FS is a well‐characterized and known hepatotoxin in both human and animal test systems. In this stu more

Market studies hypertension

• Hypertension – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Hypertension - Pipeline Review, H1 2012', provides an overview of the Hypertension therapeutic pipeline. This report provides information on the therapeutic development for Hypertension, complete with latest updates, and special features on late-stage and dis more

• Endpoints - Clinical Trials in Cardiovascular Disorders - Optimal Use of Surrogate Endpoints and Clinical Biomarkers are Key Determinants of Success

  GBI Research, the leading business intelligence provider, has released its latest research “Endpoints - Clinical Trials in Cardiovascular Disorders - Optimal Use of Surrogate Endpoints and Clinical Biomarkers are Key Determinants of Success” which provides an insight into the different endpoints tha more

• Global Intravenous (IV) Iron Drugs Market: 2011 Edition

  Iron is one of the most important minerals present in the human body and performs the task of carrying oxygen throughout the body through blood, which is then further utilized by the cells to get energy. Decline in iron can therefore lead to certain major problems. Although oral iron supplements can more

Websites hypertension