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Human Genome

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  • Ötzi’s “non-human” DNA

    Ötzi’s human genome was decoded from a hip bone sample taken from the 5,300 year old mummy. However the tiny sample weighing no more than 0.1 g provides so much more information. A team of scientists from EURAC in Bolzano/Bozen together with colleagues from the University of Vienna successfully anal more

  • Male infertility: It's all about the package

    Infertility is generally thought of as a woman's problem. In fact, more than 3 million men across America also experience it. Today, researchers from Cold Spring Harbor Laboratory (CSHL) describe a key event during sperm development that is essential for male fertility. A team led by CSHL Professor more

  • Seeing double: New study explains evolution of duplicate genes

    From time to time, living cells will accidently make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity. A new study shows one way tha more

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White papers Human Genome

  • A High-Throughput Experimental Tool for Studying Gene Pathways

    The post-genome era has lead to great advances in high-throughput genomics studies. Genomic approaches such as microarray expression analyses and Chromatin Immuno-Precipitation on Chip (ChIP-chip) transcription factor binding assays have yielded new discoveries and insights into genetic pathways. These technologies provide valuable observational data but do not identify the functional connections within networks or explain the mechanism of gene regulation. Reporter gene based experiments like functional promoter assays provide an important additional layer of data for understanding mechanisms of regulation in genetic networks. Efficient and reproducible transfection methods are a prerequisite for all of these assays involving transfections. more

  • Rapid High-Throughput Methylation Analysis Using the LightCycler® 480 System

    The LightCycler® 480 Instrument is a versatile platform for molecular studies. We assessed the performance of the instrument combined with the LightCycler® 480 High Resolution Melting Master mix for DNA methylation analysis using the methylation-sensitive high resolution melting (MS-HRM) methodology. This proved to be a robust platform for performing MS-HRM experiments, allowing rapid and high-throughput studies of DNA methylation. more

  • New Application for the LightCycler® 480 System: qPCR-based microRNA-Profiling

    Recent studies indicate that microRNAs (miRNAs) are mechanistically involved in the development of various human malignancies and therefore represent a promising new class of biomarkers. Quantitative PCR-based technologies are emerging as the gold standard for miRNA profiling. Here, a commercially available miRNA assay was used to measure and compare the expression levels of 154 miRNAs of seven lymph node samples using the LightCycler® 480 Instrument and a competitor real-time PCR system. We observed highly similar results for 134 miRNAs (87%) and some larger deviations (20 ­miRNAs/13%). In addition to large-scale miRNA profiling, it is also possible to use the LightCycler® 480 System in the assessment of miRNA expression in small sample sizes. We have conclusively demonstrated that miR-205 can be detected in a dose-dependent manner in a dilution series of 50, 10, 5, and 1 cell(s) of the KU19-19 cell line. more

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PCR molecular biology reagents kits for human veterinary and food diagnostics - Sacace Biotechnologi

Home page Add Bookmark ? About Us Our Products Real Time Real Time PCR Kits HIV and HIV Associated Infections Kits Hepatitis Viruses Kits Human Papilloma Viruses Kits Sexually Transmitted Infections Kits Herpes Viruses Kits TORCH Complex Kits Respiratory Infections Kits Neurological Infections Kits more

MammaPrint | Personalize Your Breast Cancer Treatment | Agendia

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Arena Pharmaceuticals

HOME CONTACT US SITE MAP ABOUT US PRODUCT CANDIDATES RESEARCH PROGRAMS GPCR TECHNOLOGY INVESTORS CAREERS   ARENA'S GPCR TECHNOLOGIES GPCR FAQ   GPCR Technology G protein-coupled receptors (GPCRs) are proteins located on a cell's surface. These receptors play a key role in cell to cell communication more

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GDB Human Genome Database

GDB Human Genome Database The GDB Human Genome Database is a community curated collection of human genomic data. What set GDB apart from other biological databases, was its use of world-class leaders in human genetics to act as curators for th ... more


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