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In both the male and the female the Wolffian duct develops in to the trigone of urinary bladder, a part of the bladder wall. However, further development differentiates between the sexes in the development of the urinary and reproductive organs.
In a male, it develops into a system of connected organs between the testis and the prostate, namely the rete testis, the efferent ducts, the epididymis, the vas deferens, the seminal vesicle, and the prostate.
For this it is critical that the ducts are exposed to testosterone during embryogenesis. Testosterone binds to and activates androgen receptor, affecting intracellular signals and modifying the expression of numerous genes.
In the mature male, the function of this system is to store and mature sperm, and provide accessory semen fluid.
In the female, in the absence of testosterone support, the Wolffian ducts develop and wither.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Wolffian_duct". A list of authors is available in Wikipedia.|