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Chromosomes

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  • What Holds Chromosomes Together

    All living organisms consist of cells that have arisen from other living cells by the process of cell division. In order to ensure that the genetic material is equally and accurately distributed between the two daughter cells during cell division, the DNA fibers must remain in an orderly and closely more

  • Scientists extend telomeres to slow cell aging

    Will extending telomeres lead to longer, healthier lives? Researchers have taken an important step toward answering this question by developing a new treatment used in the laboratory that extends telomeres.One of the key aspects of aging is the shortening of telomeres over time. Telomeres, which ser more

  • New tool could help reshape the limits of synthetic biology

    NYU Langone yeast geneticists report they have developed a novel tool — dubbed "the telomerator" — that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair stru more

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  • Aphidicolin-Mediated Replication Stress Induces Submicroscopic Tumor-Like Deletions in FHIT/FRA3B

    Common fragile sites (CFSs) are loci that are particularly susceptible to forming gaps and breaks on metaphase chromosomes after partial inhibition of DNA synthesis, for example induced by aphidicolin (APH). FRA3B, a fragile site lying within the FHIT tumor suppressor gene, is a site of frequent heterozygous and homozygous deletions in cancer cells and precancerous lesions. Most FHIT and other CFS-associated gene rearrangements in tumors are deletions of hundreds of kilobases often resulting in the inactivation of associated genes. However, there has been no direct evidence showing that CFS instability or replication stress can induce submicroscopic deletions like the ones found in cancer cells. Durkin et al. produced FHIT/FRA3B deletions similar to those in tumor cells by inducing replication stress in human-mouse chromosome 3 somatic hybrid cells with APH. more

  • Nobel Prize for Solving the End-Replication Problem

    The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic re more

  • Rare Variants of IFIH1 Protect Against Type-1 Diabetes

    Nejentsev and co-workers have found that rare alleles of all associated IFIH1 polymorphisms consistently protect from type-1 diabetes, whereas IFIH1 alleles carried by the majority of the population predispose to the disease. This observation suggest more

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Definition

List of number of chromosomes of various organisms

List of number of chromosomes of various organisms This page lists the numbers of Chromosome s in various plants , animals , protists , and other living organisms, given as the diploid number (2n) Sorted alphabetically *African Wild Dog 78 ... more

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