Cancer Therapy

News Cancer Therapy

• New Roche Award for antibody-based cancer therapy research
  

  In a newly created award, pRED`s Discovery Oncology unit of Roche (RHHBY) in Penzberg, Germany invites European researchers to submit abstracts which describe their scientific work in the field of tumor-selective membrane targets for antibody-based cancer therapy. The award aims to honor and support more

• Pathway controlling cell growth revealed

  A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state. The finding has revealed an important mechanism controlling the growth of rapidly-dividing cells that may ultimately lead to the development of new treatment more

• Tumour blood vessels prevent the spread of cancer cells

  A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggest more

Publications Cancer Therapy

• Systematic tracking of dysregulated modules identifies novel genes in cancer

  Motivation: Deciphering the modus operandi of dysregulated cellular mechanisms in cancer is critical to implicate novel cancer genes and develop effective anti-cancer therapies. Fundamental to this is meticulous tracking of the behavior of core modules, including complexes and pathways across speci more

• Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF‐1α and glycolysis, by inhibiting PI3K/Akt signaling pathway

  Abstract Hypoxia induced drug resistance is a major obstacle in the development of effective cancer therapy. In the present study, the reversal abilities of wogonin on the hypoxia resistance and the underlying mechanisms were discovered. MTT assay revealed that hypoxia increased maximal 1.71‐, more

• Syntetic Oligosacharides Clinical Application in Cancer Therapy

  Abstract: It is well established that glucans enhance the efficacy of anti-cancer and anti-infection immunotheraphy, both in clinical and experimental conditions. However, the considerable variations among batches of natural glucan in molecular weight, branching frequency, as well as linkag more

Market studies Cancer Therapy

• Pharmaceutical Pricing and Reimbursement in Oncology - Payer Pressure to Justify Premium Pricing of Novel Agents, Pushing Companies to Risk-Sharing Modalities

  GBI Research, leading business intelligence provider, has released its latest research report, entitled “Pharmaceutical Pricing and Reimbursement in Oncology - Payer Pressure to Justify Premium Pricing of Novel Agents, Pushing Companies to Risk-Sharing Modalities”. It provides a comprehensive overvi more

• Oncology Pharmaceuticals Market in India 2012

  Oncology pharmaceuticals market in India, a leading segment of the overall pharmaceuticals market is the fourth largest in volume and eighth largest in value in the global market. Since cancer is the second largest cause of death in the country, the Indian market is characterized by a huge demand more

• Gene Therapy Market to 2018 - Product Development Slowed by Clinical Failures, Close Regulatory Surveillance and High Compliance Standards

  GBI Research’s new report, “Gene Therapy Market to 2018 - Product Development Slowed by Clinical Failures, Close Regulatory Surveillance and High Compliance Standards”, provides in-depth analysis of the unmet needs, drivers and barriers that impact the global gene therapy market. The report analyzes more

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