New discovery could advance the fight against malaria

Key proteins for malaria reproduction found in the mosquito

17-Jun-2025 - How can the malaria pathogen be prevented from multiplying successfully? Dr. Franziska Hentzschel, a scientist at the Medical Faculty of Heidelberg University, has discovered a new approach to this. Her research is reported in the current issue of the scientific journal "Nature ...

Chlorotonil: Game-Changer in the Fight Against Multidrug-Resistant Pathogens

Researchers decipher novel mode of action of natural product antibiotic

17-Apr-2025 - The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel mode of action are urgently needed. Researchers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now uncovered ...

Epigenetic inhibitors as a promising new antimalarial intervention strategy?

A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen

21-Feb-2025 - A multinational research team led by Professor Markus Meißner (LMU Munich) and Professor Gernot Längst (University of Regensburg) has gained important insights into the gene regulation of Plasmodium falciparum, the main cause of malaria. Published in the journal Nature, the findings open up new ...

First-of-its-kind vaccine expands malaria protection for pregnant women

Sanaria® PfSPZ Vaccine protects women against malaria before and during pregnancy for at least two years

20-Aug-2024 - In a report a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable ...

Improved prognosis of malaria spread

12-Aug-2024 - An international research team involving geographers from the University of Augsburg has combined models from climate and water research and malaria transmission. In the journal "Water Resources Research", they show that both the climatic conditions for the mosquito population and the intensity ...

try coziness: Very slow malaria pathogens could be suitable as a vaccine

07-Aug-2024 - Scientists from the Heidelberg Medical Faculty at Heidelberg University, the Center for Infectious Diseases at Heidelberg University Hospital and the German Center for Infection Research have successfully tested a new approach for a malaria vaccine in animal experiments: As a vaccine, they used ...

Blood diagnostics modelled on leeches

For all those who are afraid of needles: New device for taking blood samples uses microneedles and a suction cup instead of a large needle

07-May-2024 - Researchers at ETH Zurich have developed a safe and inexpensive device for reliable blood measurements. It works using a suction cup and could also be employed to diagnose the tropical disease malaria – even by non-​medical personnel. Many people are afraid of needles, and having a doctor take a ...

How mosquito larva guts could help create highly specific insecticides

Did you know that the world’s deadliest animal is the mosquito?

10-Apr-2024 - Aedes aegypti is one of the most dangerous mosquito. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research published in the Journal of the American Chemical Society reports new molecules that label proteins in the unique, alkaline ...

AI identifies antimalarial drug as possible osteoporosis treatment

Osteoporotic mice treated with the drug had significantly improved bone density

25-Oct-2023 - Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications. Researchers reporting in ACS Central Science have used one such deep learning algorithm, and ...

How male mosquitoes compensate for having only one X chromosome

Research findings could spur new solutions to curb malaria

11-Oct-2023 - The research group of Dr Claudia Keller Valsecchi (Institute of Molecular Biology, Mainz, Germany) and their collaborators have discovered the master regulator responsible for balancing the expression of X chromosome genes between males and females in the malaria mosquito. This discovery helps ...