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Scientists investigating how the human immune system defends against malaria have uncovered a rare phenomenon: antibodies working together to bind to a vulnerable spot on the parasite. The new research shows that antibodies working together can result in a protein on the parasite's cell surface lock more
Malaria parasites of the genus Plasmodium move ten times faster through the skin than immune cells, whose job it is to capture such pathogens. Heidelberg scientists have now found a reason why the parasite is faster than its counterpart. They did this by studying actin, a protein that is important t more
Medicines given to household pets to kill fleas and ticks might be effective for preventing outbreaks of malaria, Zika fever and other dangerous insect-borne diseases that infect millions of people worldwide, according to a new study led by scientists at Calibr, a non-profit drug discovery institute more
The Nobel Prize in Physiology or Medicine 2015 goes to William Campbell & Satoshi Ōmura "for their discoveries concerning a novel therapy against infections caused by roundworm parasites" and Youyou Tu "for her discoveries concerning a novel therapy against Malaria". more
Malaria Severe malaria is caused by the parasite Plasmodium falciparum . Infections can result in organ failure and life-threatening hematological or metabolic abnormalities. Lee et al. sequenced patient and parasite transcriptomes from 46 P. falciparum –infected Gambian children to better more
Immunology Affinity maturation in B cells generates antibodies with increasingly enhanced antigen-binding properties. Imkeller et al. investigated the maturation of human B cells that express protective antibodies against the circumsporozoite protein of the malaria-causing parasite Plasmodium more
by Ninja Ritter Klejnstrup, Julie Buhl-Wiggers, Sam Jones, John Rand Malaria is a major cause of morbidity and mortality in sub-Saharan Africa. It is also a dynamic contributor to poverty through its effects on children’s cognitive development. This paper examines the degree to which malaria in e more
BMI View: Economic growth and the resulting increase in Uganda's middle-class population will lead to rising demand for quality healthcare services as incomes improve. Investment into private healthcare facilities in Uganda in order to meet the demand for services is therefore an advisable business more
Introduction Global Markets Direct’s, 'Malaria - Pipeline Review, H2 2012', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Malaria, complete with latest updates, and special features on late-stage and discontinued more
BMI View: The outlook for Zimbabwean healthcare and pharmaceuticals will be more affected by the general election in November than any industry-specific factors. Furthermore, BMI does not foresee much of an improvement in Zimbabwe’s investment environment while Zanu PF remains in power and liquidity more
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