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Mutations

News Mutations

  • First 3-D structure of DHHC enzymes reported

    The first three-dimensional structure of DHHC proteins--enzymes involved in many cellular processes, including cancer--explains how they function and may offer a blueprint for designing therapeutic drugs. Researchers have proposed blocking DHHC activity to boost the effectiveness of first-line treat more

  • Rare melanoma type highly responsive to immunotherapy

    Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients. Treatment is difficult because these tumors are often resistant to chemotherapy and lack actionable mutations commonly found in other types more

  • CRISPR treatment prevents hearing loss in mice

    Using molecular scissors wrapped in a greasy delivery package, researchers have disrupted a gene variant that leads to deafness in mice. A single treatment involving injection of a genome editing cocktail prevented progressive hearing loss in young animals that would have otherwise gone deaf, Howard more

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Events Mutations

Conference
25-03 – 30-03
2018
Ventura, US

DNA Damage, Mutation and Cancer

The 2018 Gordon Research Conference on DNA Damage, Mutation and Cancer is developed around the theme of exploiting fundamental knowledge to advance treatment and prevention. Rich and ever-increasing information is available on the specific mutations that are the molecular basis of cancer. Many mutat

Conference
25-04 – 27-04
2018
Heidelberg, DE

EMBL Conference: The Epitranscriptome

The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to posttranscriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. Furthermore

Conference
24-06 – 29-06
2018
Newry, US

Mutagenesis

The 2018 Gordon Research Conference on Mutagenesis will focus on the causes and consequences of mutagenesis, addressing topics ranging from the fundamental molecular mechanisms of mutagenesis through the roles of mutagenesis in biology and disease to the exploitation of mutagenesis and mutagenic mec

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Definition

Mutation

Mutation In biology , mutations are changes to the base pair sequence of the genetic material of an organism. Mutations can be caused by copying errors in the genetic material during cell division , by exposure to ultraviolet or ionizing ra ... more

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