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• Allumera shows significant improvements in appearance of skin compared to light

  Photocure announced positive preliminary results from its consumer trial on Allumera™, demonstrating that the product can improve the appearance of skin. The RevitAll ™ study was designed to determine the ability of Allumera™ cream to improve the appearance of skin compared to illumination by light more

• Sun Pharma Announces USFDA Tentative Approval for Generic Cymbalta

  Sun Pharmaceutical Industries Ltd. announced that USFDA has granted its subsidiary a tentative approval for an Abbreviated New Drug Application (ANDA) to market a generic version of Cymbalta®, duloxetine hydrochloride delayed-release capsules. These generic duloxetine hydrochloride delayed-release more

• Scientists at IRB Barcelona and BSC publish the world's largest video data bank of proteins

  Scientists at IRB Barcelona and BSC publish the world's largest video data bank of proteins The new database, which includes 1,700 proteins in motion, allows a more efficient design of drugs; MoDEL holds 30 percent of human therapeutic targets and the objective is to cover 80 percent in 3 years. Af more

White papers Base

• Mutation Scanning of the Cytidine Deaminase Gene by High-Resolution Melting Curve Analysis Using the LightCycler® 480 System
  

  Alexandre Evrard1,2, Caroline Raynal1,2, Jean-Christophe Boyer2, Lionel Le Gallic2, and Serge Lumbroso1,2 1Institut de Génomique Fonctionnelle, Département d'Oncologie Moléculaire et Cellulaire, Montpellier, France, 2Laboratoire de Biochimie, Hôpital Carémeau, CHU Nîmes, France *Corresponding author more

• Evolutionary Link Between Maternal Behavior and Eusociality Is Supported by Wasp Gene Expression
  

  A defining feature of eusociality is the presence of workers that abstain from reproduction and care for their siblings (i.e., workers forage for food and feed the brood). It has been proposed that this behavior evolved from maternal care behavior and that sibling care and maternal care behaviors are regulated by similiar patterns of gene regulation. Toth et al. assessed this proposal by examining gene expression in the primitively eusocial wasp Polistes metricus using 454 Sequencing; 391,157 brain cDNA reads were generated and resulted in hits to 3,017 genes from the honey bee genome. Orthologs of 32 honey bee behaviorally related genes were identified and analyzed. The gene expression in the brain of P. metricus workers was more similar to that of foundresses, which show maternal care, than to that of queens and gynes, which do not. more

• New GS FLX Titanium Series Paired End Sequencing Improved De Novo Sequencing for High Quality Genome Assembly
  

  Roche Applied Science has launched the latest update to the Genome Sequencer FLX System, the new GS FLX Titanium Library Paired End Adaptors for improved whole genome de novo sequencing. Widely recognized as the platform of choice for de novo sequencing applications, as a result of the system's long shotgun reads, the addition of 3kb, 8 kb and 20 kb span paired end libraries now facilitates assembly of increasingly complex genomes. The improved sequencing solution offers biologists more complete genome coverage, assembly into fewer, larger scaffolds and the ability to explore the full range of genetic variation more

Publications Base

• GC-Biased Gene Conversion in Yeast Is Specifically Associated with Crossovers: Molecular Mechanisms and Evolutionary Significance

  GC-biased gene conversion (gBGC) is a process associated with recombination that favors the transmission of GC alleles over AT alleles during meiosis. gBGC plays a major role in genome evolution in many eukaryotes. However, the molecular mechanisms of gBGC are still unknown. Different steps of the more

• Mitogenomic Phylogenetics of Fin Whales (Balaenoptera physalus spp.): Genetic Evidence for Revision of Subspecies

  by Frederick I. Archer, Phillip A. Morin, Brittany L. Hancock-Hanser, Kelly M. Robertson, Matthew S. Leslie, Martine Bérubé, Simone Panigada, Barbara L. Taylor There are three described subspecies of fin whales (Balaenoptera physalus): B. p. physalus Linnaeus, 1758 in the Northern Hemisphere, B. more

• Effect of heat treatment on internal atmosphere and leaf extension of minimally processed leek stalks

  Summary Leeks trimmed at 20 cm from their base were immersed in a 55 °C hot water bath. During the heat treatment (HT), the internal gases released from each stalk were collected, and their volume as well as CO2 and O2 concentrations were determined. After HT, cooling and storage at 10 °C for 8  more

Market studies Base

• Negative Pressure Wound Therapy (NPWT) Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017

  Introduction GlobalData’s new report, “Negative Pressure Wound Therapy (NPWT) Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017” provides key market data on the Negative Pressure Wound Therapy (NPWT) market in the BRICS countries. The report provides value ($m), volume (u more

• Rigid Endoscopes Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017

  Introduction GlobalData’s new report, “Rigid Endoscopes Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017” provides key market data on the Rigid Endoscopes market in the BRICS countries. The report provides value ($m), volume (units) and average price ($) data for each se more

• Pressure Relief Devices Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017

  Introduction GlobalData’s new report, “Pressure Relief Devices Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017” provides key market data on the Pressure Relief Devices market in the BRICS countries. The report provides value ($m), volume (units) and average price ($) da more

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