Novel aggregation-specific fluorogen monitors prefibrillar protein aggregation by fluorescence polarisation (FP)

Highly ordered protein aggregates, termed amyloid fibrils, are associated with a broad range of diseases, many of which are neurodegenerative

Miniaturization and Improved Throughput of the BCA Concentration Determination Method

Popular absorption assays are difficult to miniaturize. Learn how the fluorescence of a white plate helps to measure it in 10 µl

FRET sensor assesses ATP levels in living plants experiencing low oxygen conditions

To survive as sessile organisms, plants need to constantly adapt their metabolism to their environment.

Nanobret ™ -Based Assay for Internalization of cxcr4

Read how GPCRs are studied at endogenous expression levels by employing CRISPR/Cas9.

CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking

Real-Time Assessment of Apoptosis and Necrosis

Cell death is important for multicellular homeostasis but it also has an unfortunate role in human diseases

In vitro System Measures Cellular Responses to Oxygen Changes During Ischemia and Reperfusion

Microplate Reader Imitates Oxygen Removal And Recovery Of A Vascular Closure

CLARIOstar Microplate Receptor with atmospheric control unit exposes cells to custom O2 concentrations and measures cellular assays

Measuring Changes in Intracellular Metabolism

By Monitoring Extracellular Acidification and Oxygen Consumption in Real-Time

Dysregulation of cellular energy metabolism is a common factor in a variety of disorders including diabetes and obesity as well as cancer

Simultaneous Detection of GPCR Second Messengers in Living Cells

Due to their role in signal transmission from the outside to the inside of a cell, G-protein coupled receptors are prominent drug targets

Verifying SPARCL Performance on the CLARIOstar Equipped for Reading at Time of Injection

SPARCL refers to an immunoassay that does not require washing steps

Monitoring of Insulin Granule Packaging in Live Cells Using homoFRET-FP Detection

Detecting homo-FRET-FP of mCherry labelled insulin with the PHERAstar allows for monitoring of cellular insulin-granules in 384 well plate format