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Antibody Glycosylation Analysis – the Common, the Accurate and the Smart Way

On-demand webinars
Englisch
35 min

Glycosylation of the Fc region of a therapeutic antibody influences its mode of action. Glycan patterns are frequently analyzed in R&D to monitor success of Fc-optimization, in process optimization, quality control, stability testing and lot-to-lot comparison.
We present HPLC-based methods that analyze Fc glycosylation and its functional consequences. We compare them and clarify which method is suitable for which question.

Dr. Andrea Krumm

Product Manager Analytical Columns

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Dr. Andrea Krumm

Dr. Andrea Krumm

Antibody Glycosylation Analysis – the Common, the Accurate and the Smart Way

On-demand webinars
Englisch
35 min

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Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous

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HPLC is a key technology in modern analytical chemistry. It enables the separation, identification and quantification of components in complex mixtures with high precision and efficiency. Whether in the analysis of active pharmaceutical ingredients, the quality control of foodstuffs or the examination of biological samples - HPLC is often the method of choice for demanding separation tasks.

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View topic world

Topic world HPLC

HPLC is a key technology in modern analytical chemistry. It enables the separation, identification and quantification of components in complex mixtures with high precision and efficiency. Whether in the analysis of active pharmaceutical ingredients, the quality control of foodstuffs or the examination of biological samples - HPLC is often the method of choice for demanding separation tasks.

5+ products
4 whitepaper
5+ brochures