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Nothing works without the correct form: For most proteins, there are millions of ways in which these molecules, composed of long chains of amino acids, can be folded - but only one way is the right one. Researchers in the department "Cellular Biochemistry" at the Max Planck Institute for Biochemistry in Martinsried examine how this origami in cells works and what happens if something goes awry. Franz Ulrich Hartl and his team are interested in both the underlying mechanisms and the structure of the molecules involved.
Epigenetics - packaging artists in the cell
Methyl attachments to histone proteins determine the degree of packing of the DNA molecule. They thereby determine whether a gene can be read or not. In this way, environment can influence the traits of an organism over generations. more
Biomaterials - patent solutions from nature
Animals and plants can produce amazing materials such as spider webs, wood or bone using only a few raw materials available. How do they achieve this? And what can engineers learn from them? more
The discovery that bacteria use a kind of immune system to fight viruses initially was only interesting for microbiologists. But when the discovery that CRISPR/Cas9 system is able to manipulate genes of many organisms was made, also non-scientists were alerted. But how does this method works? more
An international research team headed by the Max Planck Institute for Marine Microbiology in Bremen, Aarhus University and the Science for Life Lab in Uppsala has developed tiny particles that measure the oxygen concentration in their surroundings. In this way, they can track fluid flow and ... more
New method revolutionizes cancer diagnosis
How does cancer arise? How does cellular composition influence tumor malignancy? These questions are profound and challenging to answer, but are crucial to understand the disease and find the right cure. Now, a German-Danish team led by Professor Matthias Mann has developed a ground-breakin ... more
MCM molecules impede the formation of DNA loops
The entire genomic material of a cell must be packed into a tiny cell nucleus in such a way, that on the one hand, it can be stored in an organized manner and, on the other hand, it can be transcribed, duplicated or repaired as needed. Different proteins are responsible for space-saving pac ... more
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
The research institutes of the Max Planck Society perform basic research in the interest of the general public in the natural sciences, life sciences, social sciences, and the humanities. In particular, the Max Planck Society takes up new and innovative research areas that German universiti ... more
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