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Nothing works without the correct form: For most proteins, there are millions of ways in which these molecules, composed of long chains of amino acids, can be folded - but only one way is the right one. Researchers in the department "Cellular Biochemistry" at the Max Planck Institute for Biochemistry in Martinsried examine how this origami in cells works and what happens if something goes awry. Franz Ulrich Hartl and his team are interested in both the underlying mechanisms and the structure of the molecules involved.
Epigenetics - packaging artists in the cell
Methyl attachments to histone proteins determine the degree of packing of the DNA molecule. They thereby determine whether a gene can be read or not. In this way, environment can influence the traits of an organism over generations. more
Biomaterials - patent solutions from nature
Animals and plants can produce amazing materials such as spider webs, wood or bone using only a few raw materials available. How do they achieve this? And what can engineers learn from them? more
The discovery that bacteria use a kind of immune system to fight viruses initially was only interesting for microbiologists. But when the discovery that CRISPR/Cas9 system is able to manipulate genes of many organisms was made, also non-scientists were alerted. But how does this method works? more
The Origin of Life in membraneless protocells
How life arose from non-living chemicals more than 3.5 billion years ago on Earth is one of the deepest and still unanswered scientific questions. One hypothesis (RNA world hypothesis) assumes that RNA biomolecules were key players during this time (origin of life) as they carry genetic inf ... more
Stress affects brain’s blood flow
Several imaging studies suggest a link between chronic stress and changes in brain regions that coordinate the stress response. Acute stress responses can be adaptive, but chronic stress can trigger psychiatric disorders. To help determine what shifts the balance, scientists from the Max-Pl ... more
All cells in the body have the basic ability to protect themselves from infection, called the innate immune response. But how cells do this is not very well understood. Recently, scientists from the Max Planck Institute for Biology of Ageing and the University of Cologne, found that the siz ... more
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
The research institutes of the Max Planck Society perform basic research in the interest of the general public in the natural sciences, life sciences, social sciences, and the humanities. In particular, the Max Planck Society takes up new and innovative research areas that German universiti ... more
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