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170 Newest Publications about the topic traumatic brain injuries


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From blast to bench: A translational mini‐review of posttraumatic headache

02-Feb-2017 | Laura S. Moye, Amynah A. Pradhan, Journal of Neuroscience Research, 2017

Current events within the military and professional sports have resulted in an increased recognition of the long‐term and debilitating consequences of traumatic brain injury. Mild traumatic brain injury accounts for the majority of head injuries, and posttraumatic headache is the most common ...


Challenging the dogma that ‘rest is best’ after concussion (Commentary on Mychasiuk et al.)

12-Aug-2016 | Bridgette D. Semple, European Journal of Neuroscience, 2016

Abstract Clinical management of concussions or mild traumatic brain injuries (mTBI) is currently guided by expert‐derived consensus statements (Giza etal., 2013; McCrory etal., 2013; Graham etal., 2014). At present, concussed patients are advised to undergo an initial post‐injury period of ...


Microstructural and microglial changes after repetitive mild traumatic brain injury in mice

25-Jul-2016 | Shenandoah Robinson, Jacqueline B. Berglass, Jesse L. Denson, Justin Berkner, Christopher V. Anstine, Jesse L. Winer ..., Journal of Neuroscience Research, 2016

Traumatic brain injury (TBI) is a major public health issue, with recently increased awareness of the potential long‐term sequelae of repetitive injury. Although TBI is common, objective diagnostic tools with sound neurobiological predictors of outcome are lacking. Indeed, such tools could help ...


Chronic cerebrovascular dysfunction after traumatic brain injury

27-Apr-2016 | Amandine Jullienne, Andre Obenaus, Aleksandra Ickova, Catherine Savona‐Baron, William J. Pearce, Jerome Badaut, Journal of Neuroscience Research, 2016

Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form blood vessels and that are involved in maintaining their proper function can be altered by TBI. This Review ...


MHC class I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression [RESEARCH]

01-Sep-2013 | P. Austin Nelson; Jennifer R. Sage; Suzanne C. Wood; Christopher M. Davenport; Stephan G. Anagnostaras; Lisa M. Boul ..., Learning & Memory, 2013

Memory impairment is a common feature of conditions that involve changes in inflammatory signaling in the brain, including traumatic brain injury, infection, neurodegenerative disorders, and normal aging. However, the causal importance of inflammatory mediators in cognitive impairments in these ...


Neuronal adhesion and synapse organization in recovery after brain injury

28-Aug-2013 | Kellie Park; Thomas Biederer, Future Neurology, 2013

Few specific therapeutic targets exist to manage brain injury, despite the prevalence of stroke or traumatic brain injury. With traumatic brain injury, characteristic neuronal changes include axonal swelling and degeneration, and the loss of synapses, the sites of communication between neurons. ...


Synapto-Protective Drugs Evaluation in Reconstructed Neuronal Network

16-Aug-2013 | Bérangère Deleglise et al., PLoS ONE, 2013

by Bérangère Deleglise, Benjamin Lassus, Vaneyssa Soubeyre, Aurélie Alleaume-Butaux, Johannes J. Hjorth, Maéva Vignes, Benoit Schneider, Bernard Brugg, Jean-Louis Viovy, Jean-Michel Peyrin Chronic neurodegenerative syndromes such as Alzheimer’s and Parkinson’s diseases, or acute syndromes such ...


Enhanced Cell Death Imaging Using Multivalent Zinc(II)-bis(dipicolylamine) Fluorescent Probes

05-Aug-2013 | Bryan A. Smith; Kara M. Harmatys; Shuzhang Xiao; Erin L. Cole; Adam J. Plaunt; William Wolter; Mark A. Suckow; Bradl ..., Molecular Pharmaceutics, 2013

There is a clinical need for imaging technologies that can accurately detect cell death in a multitude of pathological conditions. Zinc(II)-bis(dipicolylamine) (Zn2BDPA) coordination complexes are known to associate with the anionic phosphatidylserine that is exposed on the surface of dead and ...


The Challenge of Mild Traumatic Brain Injury: Role of Biochemical Markers in Diagnosis of Brain Damage

28-Jun-2013 | Stefania Mondello, Kara Schmid, Rachel P. Berger, Firas Kobeissy, Domenico Italiano, Andreas Jeromin, Ronal L. Hayes ..., Medicinal Research Reviews, 2013

Abstract During the past decade there has been an increasing recognition of the incidence of mild traumatic brain injury (mTBI) and a better understanding of the subtle neurological and cognitive deficits that may result from it. A substantial, albeit suboptimal, effort has been made to define ...


Pharmaceuticals, Vol. 6, Pages 788-812: Voltage-Gated Calcium Channel Antagonists and Traumatic Brain Injury

26-Jun-2013 | Gurkoff, Gene ; Shahlaie, Kiarash ; Lyeth, Bruce ; Berman, Robert, Pharmaceuticals, 2013

Traumatic brain injury (TBI) is a leading cause of death and disability in the United States. Despite more than 30 years of research, no pharmacological agents have been identified that improve neurological function following TBI. However, several lines of research described in this review ...


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