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5 Newest Publications about the topic synthesizers


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A Computational Method for Selecting Short Peptide Sequences for Inorganic Material Binding

22-Jul-2017 | Niloofar Nayebi, Sibel Cetinel, Sara Ibrahim Omar, Jack A Tuszynski, Carlo Montemagno, Proteins: Structure, Function, and Bioinformatics, 2017

Abstract Discovering or designing biofunctionalized materials with improved quality highly depends on the ability to manipulate and control the peptide‐inorganic interaction. Various peptides can be used as assemblers, synthesizers, and linkers in the material syntheses. In another context, ...


COMU: scope and limitations of the latest innovation in peptide acyl transfer reagents

25-May-2013 | Ramon Subirós‐Funosas, Lidia Nieto‐Rodriguez, Knud J. Jensen, Fernando Albericio, Journal of Peptide Science, 2013

The methodology for peptide bond formation is undergoing a continuous evolution where the main actors are being renewed. In recent years, coupling reagents based on the Oxyma scaffold, such as the uronium salt COMU, has been a groundbreaking contribution to the field. The advantages of COMU over ...


Simple and efficient automated radiosynthesis of 2‐18F‐fluoropropionic acid using solid‐phase extraction cartridges purification

30-Jul-2012 | W. Hongliang, H. Kongzhen, T. Ganghua, H. Tingting, Liang Xiang, Journal of Labelled Compounds and Radiopharmaceuticals, 2012

2‐18F‐Fluoropropionic acid (18F‐FPA), a fluorinated analog of 11C‐acetate, shows great potential for positron emission tomography (PET) imaging of prostate cancer. The present study reports a simple automated synthesis using cartridges purification, which affords 18F‐FPA suitable for human use. ...


An efficient one‐step radiosynthesis of [18F]FE‐PE2I, a PET radioligand for imaging of dopamine transporters

15-May-2012 | Vladimir Stepanov, Raisa Krasikova, Liina Raus, Olavi Loog, Jukka Hiltunen, Christer Halldin, Journal of Labelled Compounds and Radiopharmaceuticals, 2012

Abstract The aim of this study was to develop a direct fluorination method for the preparation of [18F]‐(E)‐N‐(3‐iodoprop‐2‐enyl)‐2β‐carbofluoroethoxy‐3β‐(4′‐methyl‐phenyl)nortropane ([18F]FE‐PE2I (VI). The synthesis procedure relies on the conventional Kryptofix‐mediated nucleophilic ...


Sugar synthesis speeds up

25-Aug-2010 | Richard Van Noorden, Nature, 2010

Sugar synthesis speeds up Nature 466, 1029 (2010). doi:10.1038/4661029a Author: Richard Van Noorden Automated synthesizers can make complex carbohydrates on demand.


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