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348 Newest Publications about the topic streptococcus pneumoniae


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ABC transporter content diversity in Streptococcus pneumoniae impacts competence regulation and bacteriocin production [Microbiology]

19-Jun-2018 | Charles Y. Wang; Nisha Patel; Wei-Yun Wholey; Suzanne Dawid, Proceedings of the National Academy of Sciences current issue, 2018

The opportunistic pathogen Streptococcus pneumoniae (pneumococcus) participates in horizontal gene transfer through genetic competence and produces antimicrobial peptides called “bacteriocins.” Here, we show that the competence and bacteriocin-related ABC transporters ComAB and BlpAB share the ...


Evolution via recombination: Cell-to-cell contact facilitates larger recombination events in Streptococcus pneumoniae

13-Jun-2018 | Lauren A. Cowley; Fernanda C. Petersen; Roger Junges; Med Jimson D. Jimenez; Donald A. Morrison; William P. Hanage, PLoS Genetics, 2018

by Lauren A. Cowley, Fernanda C. Petersen, Roger Junges, Med Jimson D. Jimenez, Donald A. Morrison, William P. Hanage Homologous recombination in the genetic transformation model organism Streptococcus pneumoniae is thought to be important in the adaptation and evolution of this pathogen. While ...


Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae

08-Jun-2018 | Germán E. Piñas; Nicolás M. Reinoso-Vizcaino; Nubia Y. Yandar Barahona; Paulo R. Cortes; Rosario Duran; Chandan Bada ..., PLoS Pathogens, 2018

by Germán E. Piñas, Nicolás M. Reinoso-Vizcaino, Nubia Y. Yandar Barahona, Paulo R. Cortes, Rosario Duran, Chandan Badapanda, Ankita Rathore, Dario R. Bichara, Melina B. Cian, Nadia B. Olivero, Daniel R. Perez, José Echenique Streptococcus pneumoniae is an opportunistic human bacterial pathogen ...


IL-17 can be protective or deleterious in murine pneumococcal pneumonia

29-May-2018 | Neil D. Ritchie; Ryan Ritchie; Hannah K. Bayes; Tim J. Mitchell; Tom J. Evans, PLoS Pathogens, 2018

by Neil D. Ritchie, Ryan Ritchie, Hannah K. Bayes, Tim J. Mitchell, Tom J. Evans Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection. The ...


RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization

11-May-2018 | David G. Glanville; Lanlan Han; Andrew F. Maule; Alexandra Woodacre; Devsaagar Thanki; Iman Tajer Abdullah; Julie A. ..., PLoS Pathogens, 2018

by David G. Glanville, Lanlan Han, Andrew F. Maule, Alexandra Woodacre, Devsaagar Thanki, Iman Tajer Abdullah, Julie A. Morrissey, Thomas B. Clarke, Hasan Yesilkaya, Nicholas R. Silvaggi, Andrew T. Ulijasz To survive diverse host environments, the human pathogen Streptococcus pneumoniae must ...


Pharmacokinetics of a novel human intravenous immunoglobulin 10% in patients with primary immunodeficiency diseases: Analysis of a phase III, multicentre, prospective, open-label study

06-May-2018 | Author(s): Isaac R. Melamed, Michael Borte, Laurenz Trawnicek, Ai-Lan Kobayashi, Roger H. Kobayashi, Alan ..., European Journal of Pharmaceutical Science, 2018

Publication date: 15 June 2018 Source:European Journal of Pharmaceutical Sciences, Volume 118 Author(s): Isaac R. Melamed, Michael Borte, Laurenz Trawnicek, Ai-Lan Kobayashi, Roger H. Kobayashi, Alan Knutsen, Sudhir Gupta, William Smits, Anna Pituch-Noworolska, Magdalena ...


Streptococcus pneumoniae: transmission, colonization and invasion

29-Mar-2018 | Jeffrey N. Weiser; Daniela M. Ferreira; James C. Paton, Nature Reviews Microbiology, 2018

Streptococcus pneumoniae has a complex relationship with its obligate human host. On the one hand, the pneumococci are highly adapted commensals, and their main reservoir on the mucosal surface of the upper airways of carriers enables transmission. On the other hand, they can cause severe disease ...


Epidemiology and clinical profile of pathogens responsible for the hospitalization of children in Sousse area, Tunisia

17-Nov-2017 | Ines Brini; Aida Guerrero; Naila Hannachi; Jihene Bouguila; Dorothea Orth-Höller; Amira Bouhlel; Lamia Boughamoura; ..., PLoS ONE, 2017

by Ines Brini, Aida Guerrero, Naila Hannachi, Jihene Bouguila, Dorothea Orth-Höller, Amira Bouhlel, Lamia Boughamoura, Benjamin Hetzer, Wegene Borena, Britta Schiela, Dorothee Von Laer, Jalel Boukadida, Heribert Stoiber This study aimed to identify a broad spectrum of respiratory pathogens from ...


Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5 [Medical Sciences]

17-Oct-2017 | Marilda P. Lisboa; Naeem Khan; Christopher Martin; Fei-Fei Xu; Katrin Reppe; Andreas Geissner; Subramanian Govindan; ..., Proceedings of the National Academy of Sciences current issue, 2017

Glycoconjugate vaccines based on isolated capsular polysaccharide (CPS) save millions of lives annually by preventing invasive pneumococcal disease caused by Streptococcus pneumoniae. Some components of the S. pneumoniae glycoconjugate vaccine Prevnar13 that contains CPS antigens from 13 ...


Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

25-Aug-2017 | Anukul T. Shenoy; Terry Brissac; Ryan P. Gilley; Nikhil Kumar; Yong Wang; Norberto Gonzalez-Juarbe; Whitney S. Hinkl ..., PLoS Pathogens, 2017

by Anukul T. Shenoy, Terry Brissac, Ryan P. Gilley, Nikhil Kumar, Yong Wang, Norberto Gonzalez-Juarbe, Whitney S. Hinkle, Sean C. Daugherty, Amol C. Shetty, Sandra Ott, Luke J. Tallon, Jessy Deshane, Hervé Tettelin, Carlos J. Orihuela For over 130 years, invasive pneumococcal disease has been ...


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