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9,725 Newest Publications about the topic plasma

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Pharmacokinetics of pericyte involvement in small-molecular drug transport across the blood-brain barrier

01-Jul-2018 | Author(s): Nebojsa Mihajlica, Christer Betsholtz, Margareta Hammarlund-Udenaes, European Journal of Pharmaceutical Science, 2018

Publication date: 15 September 2018 Source:European Journal of Pharmaceutical Sciences, Volume 122 Author(s): Nebojsa Mihajlica, Christer Betsholtz, Margareta Hammarlund-Udenaes Pericytes are perivascular cells that play important roles in the regulation of the blood-brain barrier ...

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Optimization of nanostructured lipid carriers for Zidovudine delivery using a microwave-assisted production method

01-Jul-2018 | Author(s): S.M.T. Cavalcanti, C. Nunes, S.A. Costa Lima, J.L. Soares-Sobrinho, S. Reis, European Journal of Pharmaceutical Science, 2018

Publication date: 15 September 2018 Source:European Journal of Pharmaceutical Sciences, Volume 122 Author(s): S.M.T. Cavalcanti, C. Nunes, S.A. Costa Lima, J.L. Soares-Sobrinho, S. Reis An adapted methodology for obtaining lipid nanoparticles that only uses the microwave reactor ...

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A classification modeling approach for determining metabolite signatures in osteoarthritis

29-Jun-2018 | Jason S. Rockel; Weidong Zhang; Konstantin Shestopaloff; Sergei Likhodii; Guang Sun; Andrew Furey; Edward Randell; K ..., PLoS ONE, 2018

by Jason S. Rockel, Weidong Zhang, Konstantin Shestopaloff, Sergei Likhodii, Guang Sun, Andrew Furey, Edward Randell, Kala Sundararajan, Rajiv Gandhi, Guangju Zhai, Mohit Kapoor Multiple factors can help predict knee osteoarthritis (OA) patients from healthy individuals, including age, sex, and ...

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Enhancing radiosensitivity of melanoma cells through very high dose rate pulses released by a plasma focus device

29-Jun-2018 | Francesca Buontempo; Ester Orsini; Isabella Zironi; Lorenzo Isolan; Alessandra Cappellini; Stefania Rapino; Agostino ..., PLoS ONE, 2018

by Francesca Buontempo, Ester Orsini, Isabella Zironi, Lorenzo Isolan, Alessandra Cappellini, Stefania Rapino, Agostino Tartari, Domiziano Mostacci, Giorgio Cucchi, Alberto Maria Martelli, Marco Sumini, Gastone Castellani Radiation therapy is a useful and standard tumor treatment strategy. ...

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Marine Drugs, Vol. 16, Pages 224: Pufferfish Saxitoxin and Tetrodotoxin Binding Protein (PSTBP) Analogues in the Blood Plasma of the Pufferfish Arothron nigropunctatus, A. hispidus, A. manilensis, and Chelonodon patoca

29-Jun-2018 | Yotsu-Yamashita, Mari ; Nagaoka, Yuuma ; Muramoto, Koji ; Cho, Yuko ; Konoki, Keiichi, Marine Drugs, 2018

Marine Drugs, Vol. 16, Pages 224: Pufferfish Saxitoxin and Tetrodotoxin Binding Protein (PSTBP) Analogues in the Blood Plasma of the Pufferfish Arothron nigropunctatus, A. hispidus, A. manilensis, and Chelonodon patoca Marine Drugs doi: 10.3390/md16070224 Authors: Mari ...

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A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase [Medical Sciences]

26-Jun-2018 | Kristian K. Kristensen; Søren Roi Midtgaard; Simon Mysling; Oleg Kovrov; Lars Bo Hansen; Nicholas Skar-Gislinge; Ann ..., Proceedings of the National Academy of Sciences current issue, 2018

Dietary fats absorbed by intestinal enterocytes are packaged into chylomicrons, which circulate in the bloodstream until docking along capillary endothelial cells, primarily in striated muscle and adipose tissue. There, a functional unit composed of lipoprotein lipase (LPL) and GPIHBP1 hydrolyzes ...

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High-resolution {mu}CT of a mouse embryo using a compact laser-driven X-ray betatron source [Applied Physical Sciences]

19-Jun-2018 | Jason M. Cole; Daniel R. Symes; Nelson C. Lopes; Jonathan C. Wood; Kristjan Poder; Saleh Alatabi; Stanley W. Botchwa ..., Proceedings of the National Academy of Sciences current issue, 2018

High-resolution microcomputed tomography with benchtop X-ray sources requires long scan times because of the heat load limitation on the anode. We present an alternative, high-brightness plasma-based X-ray source that does not suffer from this restriction. A demonstration of tomography of a ...

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Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats

14-Jun-2018 | Hadir M. Maher; Nourah Z. Alzoman; Shereen M. Shehata; Norah O. Abanmy, PLoS ONE, 2018

by Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Norah O. Abanmy Dasatinib (DAS) is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia and in the management of ulcerative colitis (UC). Since some nutraceuticals (e.g. curcumin, olive oil, and cocoa ...

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Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes

14-Jun-2018 | Sulav Duwal; Laura Dickinson; Saye Khoo; Max von Kleist, PLoS Computational Biology, 2018

by Sulav Duwal, Laura Dickinson, Saye Khoo, Max von Kleist To achieve the 90-90-90 goals set by UNAIDS, the number of new HIV infections needs to decrease to approximately 500,000 by 2020. One of the ‘five pillars’ to achieve this goal is pre-exposure prophylaxis (PrEP). Truvada ...

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Role of CD40 and ADAMTS13 in von Willebrand factor-mediated endothelial cell-platelet-monocyte interaction [Medical Sciences]

12-Jun-2018 | Miruna Popa; Sibgha Tahir; Julia Elrod; Su Hwan Kim; Florian Leuschner; Thorsten Kessler; Peter Bugert; Ulrich Pohl; ..., Proceedings of the National Academy of Sciences current issue, 2018

In this study we have identified a mechanism that links pathophysiological ADAMTS13 deficiency to innate immunity and hemostasis by facilitating monocyte extravasation as a prerequisite for their subsequent on-site differentiation into proinflammatory macrophages under conditions of both ...

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