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605 Newest Publications about the topic oligonucleotides


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Glycosylated cell-penetrating peptides and their conjugates to a proapoptotic peptide: preparation by click chemistry and cell viability studies

09-Nov-2009 | Laurence Dutot, Pascaline Lécorché, Fabienne Burlina, Rodrigue Marquant, Vanessa Point, Sandrine Sagan, Gérard Chass ..., Journal of Chemical Biology, 2009

Cell-penetrating peptides (CPPs), which are usually short basic peptides, are able to cross cell membranes and convey bioactive cargoes inside cells. CPPs have been widely used to deliver inside cells peptides, proteins, and oligonucleotides; however, their entry mechanisms still remain ...


A strain of Fusarium kyushuense is able to produce aflatoxin B1 and G1

25-Jul-2009 | Markus Schmidt-Heydt, Sabine Häckel, Corinna E. Rüfer, Rolf Geisen, Mycotoxin Research, 2009

A strain of F. kyushuense is able to produce aflatoxin B1 and G1 under certain growth conditions. This was ultimately demonstrated by LC-MS analysis. By using a microarray covering oligonucleotides specific for the aflatoxin pathway genes of A. flavus, the expression of homologues of nearly the ...


Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo

18-Mar-2009 | David R. Brigstock, Journal of Cell Communication and Signaling, 2009

Connective tissue growth factor (CCN2) is a major pro-fibrotic factor that frequently acts downstream of transforming growth factor beta (TGF-β)-mediated fibrogenic pathways. Much of our knowledge of CCN2 in fibrosis has come from studies in which its production or activity have been ...


Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-κB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications

14-May-2008 | Chi-Shu Sun, Kuan-Ta Wu, Hao-Hsien Lee, Yih-Huei Uen, Yu-Feng Tian, Cheng-Chen Tzeng, Andrew H.-J. Wang, Chia-Ju Che ..., Journal of Biomedical Science, 2008

The link of proto-oncogenic protein Wnt-1 production with NF-κB activation has been functionally demonstrated in PC12 cells, a rat pheochromocytoma cell line of neural crest lineage, while it is not yet verified in human cells. The link can be indirectly supported in our previous report that ...


Use of PCR to detect infection of differentially susceptible maize cultivars using Ustilago maydis strains of variable virulence

01-Jun-2003 | Alfredo D. Martínez-Espinoza, Claudia G. León-Ramírez, Nisha Singh, José Ruiz-Herrera, International Microbiology, 2003

Ustilago maydis was specifically detected in infected maize plants by means of the polymerase chain reaction (PCR) using oligonucleotides corresponding to a specific region downstream of the homeodomain of the bE genes of the pathogen. The reaction gave rise to amplification of a ca. 500-bp ...


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