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124 Newest Publications about the topic nerve cells


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Stochastic shielding and edge importance for Markov chains with timescale separation

18-Jun-2018 | Deena R. Schmidt; Roberto F. Galán; Peter J. Thomas, PLoS Computational Biology, 2018

by Deena R. Schmidt, Roberto F. Galán, Peter J. Thomas Nerve cells produce electrical impulses (“spikes”) through the coordinated opening and closing of ion channels. Markov processes with voltage-dependent transition rates capture the stochasticity of spike generation at the cost of complex, ...


A biophysical mechanism for preferred direction enhancement in fly motion vision

13-Jun-2018 | Alexander Borst, PLoS Computational Biology, 2018

by Alexander Borst Seeing the direction of motion is essential for survival of all sighted animals. Consequently, nerve cells that respond to visual stimuli moving in one but not in the opposite direction, so-called ‘direction-selective’ neurons, are found abundantly. In general, direction ...


New copies of old gene drove brain expansion

01-Jun-2018 | Elizabeth Pennisi, Science , 2018

Three nearly identical genes could help explain why the ancestral human brain tripled in size over the course of human evolution. The genes, descendants of an ancient developmental gene that multiplied and changed over time, could also explain how brain development sometimes goes wrong, leading ...


Frequency‐dependent regulation of intrinsic excitability by voltage‐activated membrane conductances, computational modeling and dynamic clamp

13-Oct-2017 | Attila Szűcs, Anikó Rátkai, Katalin Schlett, Ramon Huerta, European Journal of Neuroscience, 2017

Abstract As one of the most unique properties of nerve cells, their intrinsic excitability allows them to transform synaptic inputs into action potentials. This process reflects a complex interplay between the synaptic inputs and the voltage‐dependent membrane currents of the postsynaptic ...


Exploring the potential of natural and synthetic neuroprotective steroids against neurodegenerative disorders: A literature review

11-Jul-2017 | Ranju Bansal, Ranjit Singh, Medicinal Research Reviews, 2017

Abstract Neurodegeneration is a complex process, which leads to progressive brain damage due to loss of neurons. Despite exhaustive research, the cause of neuronal loss in various degenerative disorders is not entirely understood. Neuroprotective steroids constitute an important line of ...


Mysterious unchanging DNA finds a purpose in life

02-Jun-2017 | Elizabeth Pennisi, Science , 2017

Genome scientists have solved a long-standing mystery about ultraconserved regions of our genome. Computational scientists first identified these anomalous stretches of DNA in 2004, by comparing the genomes of diverse mammals, finding481 genome segments, 200 to more than 700 bases long, that ...


Marine Drugs, Vol. 15, Pages 101: The Influence of Tetrodotoxin (TTX) on the Distribution and Chemical Coding of Caudal Mesenteric Ganglion (CaMG) Neurons Supplying the Porcine Urinary Bladder

30-Mar-2017 | Lepiarczyk, Ewa ; Bossowska, Agnieszka ; Kaleczyc, Jerzy ; Majewska, Marta ; Gonkowski, Sławomir ; Majewski, Mariusz, Marine Drugs, 2017

The treatment of micturition disorders creates a serious problem for urologists. Recently, new therapeutic agents, such as neurotoxins, are being considered for the therapy of urological patients. The present study investigated the chemical coding of caudal mesenteric ganglion (CaMG) neurons ...


From single cells & single columns to cortical networks dendritic excitability,coincidence detection and synaptic transmission in brain slices and brains

31-Jan-2017 | Bert Sakmann, Experimental Physiology, 2017

Abstract While patch pipettes were initially designed to record extracellularly elementary current events from muscle and neuron membrane, the whole‐cell (eg Sakmann, 1992) and loose cell‐attached recording configurations proved to be useful tools for examining signaling within and between ...


Inhibitory mechanism of L‐Glutamic acid on spawning of the starfish Patiria (Asterina) pectinifera

22-Dec-2016 | Masatoshi Mita, Molecular Reproduction and Development, 2016

Abstract L‐Glutamic acid was previously identified as an inhibitor of spawning in the starfish Patiria (Asterina) pectinifera; this study examined how L‐glutamic acid works. Oocyte release from ovaries of P. pectinifera occurred after germinal vesicle breakdown (GVBD) and follicular envelope ...


Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception

06-Dec-2016 | Deborah Chiabrando; Marco Castori; Maja di Rocco; Martin Ungelenk; Sebastian Gießelmann; Matteo Di Capua; Annalisa M ..., PLoS Genetics, 2016

by Deborah Chiabrando, Marco Castori, Maja di Rocco, Martin Ungelenk, Sebastian Gießelmann, Matteo Di Capua, Annalisa Madeo, Paola Grammatico, Sophie Bartsch, Christian A. Hübner, Fiorella Altruda, Lorenzo Silengo, Emanuela Tolosano, Ingo Kurth Pain is necessary to alert us to actual or ...


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