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243 Newest Publications about the topic migraine

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25-May-2018 | American Association for the Advancement of Science, Science , 2018

SCI COMMUNIn science news around the world, the U.S. Food and Drug Administration approves the first drug to prevent migraine headaches. Swedish universities and research institutes cancel their contract with academic publishing giant Elsevier after seeking "sustainable" pricing and open access ...

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CGRP as the target of new migraine therapies — successful translation from bench to clinic

24-Apr-2018 | Lars Edvinsson; Kristian Agmund Haanes; Karin Warfvinge; Diana N. Krause, Nature Clinical Practice Neurology, 2018

Treatment of migraine is on the cusp of a new era with the development of drugs that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its receptor. Several of these drugs are expected to receive approval for use in migraine headache in 2018 and ...

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Migraine drug race turns its final corner, FDA decisions in sight

06-Mar-2018 | Elie Dolgin, Nature Biotechnology, 2018

Nature Biotechnology 36, 207 (2018). doi:10.1038/nbt0318-207 Author: Elie Dolgin

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Salmon calcitonin ameliorates migraine pain through modulation of CGRP release and dural mast cell degranulation in rats

18-Jan-2018 | Erkan Kilinc, Yasar Dagistan, Aysel Kukner, Bayram Yilmaz, Sami Agus, Gizem Soyler, Fatma Tore, Clinical and Experimental Pharmacology and Physiology, 2018

Abstract The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this study, we explored the mechanisms underlying the analgesic ...

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Migraine with aura and persistent foramen ovale

08-Dec-2017 | P T Wilmshurst, Eye, 2017

Migraine with aura and persistent foramen ovale Migraine with aura and persistent foramen ovale, Published online: 08 December 2017; doi:10.1038/eye.2017.269 Migraine with aura and persistent foramen ovale

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The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization

12-Oct-2017 | Niklas Hübel; Mahshid S. Hosseini-Zare; Jokūbas Žiburkus; Ghanim Ullah, PLoS Computational Biology, 2017

by Niklas Hübel, Mahshid S. Hosseini-Zare, Jokūbas Žiburkus, Ghanim Ullah Simultaneous changes in ion concentrations, glutamate, and cell volume together with exchange of matter between cell network and vasculature are ubiquitous in numerous brain pathologies. A complete understanding of ...

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Human models of migraine — short-term pain for long-term gain

06-Oct-2017 | Messoud Ashina; Jakob Møller Hansen; Bára Oladóttir á Dunga; Jes Olesen, Nature Clinical Practice Neurology, 2017

Human models of migraine — short-term pain for long-term gain Nature Reviews Neurology, Published online: 6 October 2017; doi:10.1038/nrneurol.2017.137 In the ongoing search for new and better migraine treatments, human models have a key role in the discovery of novel targets for antimigraine ...

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Human models of migraine — short-term pain for long-term gain

06-Oct-2017 | Messoud Ashina; Jakob Møller Hansen; Bára Oladóttir á Dunga; Jes Olesen, Nature Clinical Practice Neurology, 2017

Human models of migraine — short-term pain for long-term gain Nature Reviews Neurology, Published online: 6 October 2017; doi:10.1038/nrneurol.2017.137 In the ongoing search for new and better migraine treatments, human models have a key role in the discovery of novel targets for antimigraine ...

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A retrospective cost-analysis of additional homeopathic treatment in Germany: Long-term economic outcomes

15-Sep-2017 | Julia K. Ostermann; Claudia M. Witt; Thomas Reinhold, PLoS ONE, 2017

by Julia K. Ostermann, Claudia M. Witt, Thomas Reinhold Objectives This study aimed to provide a long-term cost comparison of patients using additional homeopathic treatment (homeopathy group) with patients using usual care (control group) over an observation period of 33 months. Methods ...

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Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction

05-Sep-2017 | Nicolas Ivan Bertone, Ayelén Ivana Groisman, Graciela Lujan Mazzone, Raquel Cano, Lucia Tabares, Osvaldo Daniel Uchitel, Synapse, 2017

Abstract Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells. We combined fluorescent FM styryl dyes and electrophysiological techniques at ex vivo levator ...

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