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1,439 Newest Publications about the topic microbes

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Within-patient mutation frequencies reveal fitness costs of CpG dinucleotides and drastic amino acid changes in HIV

28-Jun-2018 | Kristof Theys; Alison F. Feder; Maoz Gelbart; Marion Hartl; Adi Stern; Pleuni S. Pennings, PLoS Genetics, 2018

by Kristof Theys, Alison F. Feder, Maoz Gelbart, Marion Hartl, Adi Stern, Pleuni S. Pennings HIV has a high mutation rate, which contributes to its ability to evolve quickly. However, we know little about the fitness costs of individual HIV mutations in vivo, their distribution and the ...

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Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa

27-Jun-2018 | Nagel, Tobi E., Viruses, 2018

Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa Viruses doi: 10.3390/v10070345 Authors: Tobi E. Nagel The antimicrobial resistance (AMR) crisis and HIV/AIDS epidemic ...

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PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis

21-Jun-2018 | Eusondia Arnett; Ashlee M. Weaver; Kiersten C. Woodyard; Maria J. Montoya; Michael Li; Ky V. Hoang; Andrew Hayhurst; ..., PLoS Pathogens, 2018

by Eusondia Arnett, Ashlee M. Weaver, Kiersten C. Woodyard, Maria J. Montoya, Michael Li, Ky V. Hoang, Andrew Hayhurst, Abul K. Azad, Larry S. Schlesinger Peroxisome proliferator-activated receptor (PPAR)γ is a global transcriptional regulator associated with anti-inflammatory actions. It is ...

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Marine Drugs, Vol. 16, Pages 207: The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology

13-Jun-2018 | R. L. Morlighem, Jean-Étienne ; Huang, Chen ; Liao, Qiwen ; Braga Gomes, Paula ; Daniel Pérez, Carlos ; de Brandão P ..., Marine Drugs, 2018

Marine Drugs, Vol. 16, Pages 207: The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology Marine Drugs doi: ...

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Latent environment allocation of microbial community data

06-Jun-2018 | Koichi Higashi; Shinya Suzuki; Shin Kurosawa; Hiroshi Mori; Ken Kurokawa, PLoS Computational Biology, 2018

by Koichi Higashi, Shinya Suzuki, Shin Kurosawa, Hiroshi Mori, Ken Kurokawa As data for microbial community structures found in various environments has increased, studies have examined the relationship between environmental labels given to retrieved microbial samples and their community ...

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MYB72-dependent coumarin exudation shapes root microbiome assembly to promote plant health [Plant Biology]

29-May-2018 | Ioannis A. Stringlis; Ke Yu; Kirstin Feussner; Ronnie de Jonge; Sietske Van Bentum; Marcel C. Van Verk; Roeland L. B ..., Proceedings of the National Academy of Sciences current issue, 2018

Plant roots nurture a large diversity of soil microbes via exudation of chemical compounds into the rhizosphere. In turn, beneficial root microbiota promote plant growth and immunity. The root-specific transcription factor MYB72 has emerged as a central regulator in this process. Here, we show ...

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Root-exuded coumarin shapes the root microbiome [Plant Biology]

29-May-2018 | Derek S. Lundberg; Paulo J. P. L. Teixeira, Proceedings of the National Academy of Sciences current issue, 2018

Roots of land plants grow through soil, one of the most microbially rich and diverse environments on earth (1). A long history of work has revealed that plant roots interact with these microbes and help establish microbial communities distinct from the surrounding soil (2). This is partly because ...

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Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a) [Biophysics and Computational Biology]

22-May-2018 | Digvijay Singh; John Mallon; Anustup Poddar; Yanbo Wang; Ramreddy Tippana; Olivia Yang; Scott Bailey; Taekjip Ha, Proceedings of the National Academy of Sciences current issue, 2018

Adaptive immunity against foreign DNA elements in microbes, conferred by their CRISPR systems, has been repurposed for wide-ranging genome-engineering applications. The CRISPR-Cas9 system has been the most widely used system. But to overcome some of its major limitations, the search for novel ...

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Ribosomes on the night shift

18-May-2018 | Michel Nofal; Joshua D. Rabinowitz, Science , 2018

From an evolutionary perspective, life involves two simple goals: survival and reproduction. But these goals are fundamentally at odds. Reproduction depends on growth, but attempts to grow when nutrients are scarce can jeopardize survival. In cells, growth is accomplished in large part by ...

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Symbiotic root infections in Medicago truncatula require remorin-mediated receptor stabilization in membrane nanodomains [Plant Biology]

15-May-2018 | Pengbo Liang; Thomas F. Stratil; Claudia Popp; Macarena Marín; Jessica Folgmann; Kirankumar S. Mysore; Jiangqi Wen; ..., Proceedings of the National Academy of Sciences current issue, 2018

Pattern recognition receptors control the cellular entry of pathogenic as well as symbiotic microbes. While ligand-induced changes in receptor mobility at the plasma membrane and their localization in membrane nanodomains are general features, the molecular mechanism and the biological relevance ...

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