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3,264 Newest Publications about the topic metabolic diseases


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Sociodemographic determinants and health outcome variation in individuals with type 1 diabetes mellitus: A register-based study

29-Jun-2018 | Carl Willers; Hanna Iderberg; Mette Axelsen; Tobias Dahlström; Bettina Julin; Janeth Leksell; Agneta Lindberg; Peter ..., PLoS ONE, 2018

by Carl Willers, Hanna Iderberg, Mette Axelsen, Tobias Dahlström, Bettina Julin, Janeth Leksell, Agneta Lindberg, Peter Lindgren, Karin Looström Muth, Ann-Marie Svensson, Mikael Lilja Background Socioeconomic status, origin or demographic attributes shall not determine the quality of healthcare ...


Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes [Medical Sciences]

26-Jun-2018 | Yunxiao Zhu; Zdravka Cankova; Marta Iwanaszko; Sheridan Lichtor; Milan Mrksich; Guillermo A. Ameer, Proceedings of the National Academy of Sciences current issue, 2018

The clinical management of nonhealing ulcers requires advanced materials that improve wound-closure rates without relying on the release of drugs or other growth factors that could potentially lead to concerns regarding systemic deleterious side effects. We report the synthesis, characterization, ...


NIH kills alcohol trial, starts hunt for other suspect studies

22-Jun-2018 | Meredith Wadman, Science , 2018

The U.S. National Institutes of Health (NIH) in Bethesda, Maryland, last week killed a huge clinical trial probing the potential benefits of moderate drinking after an investigation found that senior officials at the agency's alcohol institute secretly and improperly wooed the alcoholic beverage ...


Can ultrasound measures of intrinsic foot muscles and plantar soft tissues predict future diabetes-related foot disease? A systematic review

15-Jun-2018 | Troy Morrison; Sara Jones; Ryan S. Causby; Kerry Thoirs, PLoS ONE, 2018

by Troy Morrison, Sara Jones, Ryan S. Causby, Kerry Thoirs Introduction Diabetes mellitus (DM) is associated with hyperglycaemia and advanced glycosylation end-products. In the foot, the consequences of chronic or uncontrolled diabetes are micro and macrovascular disease, neuropathy, reduced ...


Correction for Spence et al., Revealing the specificity of regulatory T cells in murine autoimmune diabetes [Correction]

12-Jun-2018 | National Academy of Sciences, Proceedings of the National Academy of Sciences current issue, 2018

IMMUNOLOGY AND INFLAMMATION Correction for “Revealing the specificity of regulatory T cells in murine autoimmune diabetes,” by Allyson Spence, Whitney Purtha, Janice Tam, Shen Dong, Youmin Kim, Chia-Hsin Ju, Teague Sterling, Maki Nakayama, William H. Robinson, Jeffrey A. Bluestone, Mark S. ...


CK1{delta}/ϵ protein kinase primes the PER2 circadian phosphoswitch [Cell Biology]

05-Jun-2018 | Rajesh Narasimamurthy; Sabrina R. Hunt; Yining Lu; Jean-Michel Fustin; Hitoshi Okamura; Carrie L. Partch; Daniel B. ..., Proceedings of the National Academy of Sciences current issue, 2018

Our innate circadian clocks control myriad aspects of behavior and physiology. Disruption of our clocks by shift work, jet lag, or inherited mutation leads to metabolic dysregulation and contributes to diseases, including diabetes and cancer. A central step in clock control is phosphorylation of ...


Repurposing of sodium valproate in colon cancer associated with diabetes mellitus: Role of HDAC inhibition

03-Jun-2018 | Author(s): Mayur M. Patel, Bhoomika M. Patel, European Journal of Pharmaceutical Science, 2018

Publication date: 30 August 2018 Source:European Journal of Pharmaceutical Sciences, Volume 121 Author(s): Mayur M. Patel, Bhoomika M. Patel Background and purpose Diabetic patients are at greater risk for colon cancer. Histone deacetylases (HDACs) serve as common target for both. The ...


A stimulating therapy for diabetes

25-May-2018 | Stella Hurtley; Mattia Maroso, Science , 2018

Diabetes In type 2 diabetes, insulin resistance leads to elevated blood glucose and increased risk of cardiovascular disorders. The brain participates in glucose metabolism, but whether and how modulation of brain activity affects systemic blood concentrations of glucose is poorly understood. In


Seamless recording of glucometer measurements among older experienced diabetic patients – A study of perception and usability

25-May-2018 | Peter Rasche; Alexander Mertens; Talya Miron-Shatz; Corinne Berzon; Christopher M. Schlick; Michael Jahn; Stefan Becker, PLoS ONE, 2018

by Peter Rasche, Alexander Mertens, Talya Miron-Shatz, Corinne Berzon, Christopher M. Schlick, Michael Jahn, Stefan Becker Self-measurement and documentation of blood-glucose are critical elements of diabetes management, particularly in regimes including insulin. In this study, we analyze the ...


Involvement of ciliary neurotrophic factor in early diabetic retinal neuropathy in streptozotocin-induced diabetic rats

23-May-2018 | Mingming Ma; Yupeng Xu; Shuyu Xiong; Jian Zhang; Qing Gu; Bilian Ke; Xun Xu, Eye, 2018

Ciliary neurotrophic factor (CNTF) has been evaluated as a candidate therapeutic agent for diabetes and its neural complications. However, its role in diabetic retinopathy has not been fully elucidated. This is a randomized unblinded animal experiment. Wistar rats with streptozocin (STZ)-induced ...


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