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665 Newest Publications about the topic heart failures


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Utilization of cardiac monitoring tests in women with nonmetastatic breast cancer treated with trastuzumab

10-Sep-2013 | Jaekyu Shin; Su-Ying Liang; Michael J Hassett; Kathryn A Phillips; Jennifer S Haas, Personalized Medicine, 2013

Aims: Trastuzumab, one of the best known examples of personalized medicine, requires regular cardiac monitoring because it can cause heart failure. We aimed to assess the utilization of cardiac monitoring in women with nonmetastatic breast cancer receiving trastuzumab-based chemotherapy in ...


Skeletal muscle capillary function: contemporary observations and novel hypotheses

09-Sep-2013 | David C. Poole, Steven W. Copp, Scott K. Ferguson, Timothy I. Musch, Experimental Physiology, 2013

Abstract  The capillary bed constitutes a vast surface facilitating exchange of O2, substrates and metabolites between blood and organs. In contracting skeletal muscle capillary blood flow and O2 diffusing capacity as well as O2 flux may increase two orders of magnitude above resting. Chronic ...


Value of Serial Heart Rate Variability Measurement for Prediction of Appropriate ICD Discharge in Patients with Heart Failure

06-Sep-2013 | JUDITH N. TEN SANDE, PETER DAMMAN, JAN G.P. TIJSSEN, JORIS R. DE GROOT, REINOUD E. KNOPS, ARTHUR A.M. WILDE, PASCAL ..., Journal of Cardiovascular Electrophysiology, 2013

Abstract Introduction Decreased heart rate variability (HRV) is associated with adverse outcomes in patients with heart failure. Our objective was to examine whether decreased HRV predicts appropriate implantable cardioverter defibrillator (ICD) shocks. Methods and results In 105 ...


Identification of micro‐RNA networks in end‐stage heart failure because of dilated cardiomyopathy

03-Sep-2013 | Xiaoming Zhu, Hongjiang Wang, Fan Liu, Li Chen, Weijia Luo, Pixiong Su, Weiming Li, Liping Yu, Xinchun Yang, Jun Cai, Journal of Cellular and Molecular Medicine, 2013

Abstract Micro‐RNAs regulate gene expression by directly binding to the target mRNAs. The goal of the study was to examine the expression profiling of miRNAs in human failing hearts and identify the key miRNAs that regulate molecular signalling networks and thus contribute to this pathological ...


Results from A 12 Months, Randomized, Clinical Trial Comparing an Olmesartan/Amlodipine Single Pill Combination to Olmesartan and Amlodipine Monotherapies on Blood Pressure and Inflammation

02-Sep-2013 | Author(s): Giuseppe Derosa , Arrigo F.G. Cicero , Anna Carbone , Fabrizio Querci , Elena Fogari , Angela D’Ang ..., European Journal of Pharmaceutical Science, 2013

Publication date: Available online 30 August 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Giuseppe Derosa , Arrigo F.G. Cicero , Anna Carbone , Fabrizio Querci , Elena Fogari , Angela D’Angelo , Pamela Maffioli Aim hypertension affects nearly 1 in 3 adults in ...


MicroRNA-150 aggravates H2O2-induced cardiac myocyte injury by down-regulating c-myb gene

01-Sep-2013 | Xuebiao Li; Minjian Kong; Daming Jiang; Jianfang Qian; Qunjun Duan; Aiqiang Dong, Acta Biochimica et Biophysica Sinica, 2013

MicroRNAs (miRNAs) are one class of non-coding RNAs that play an important role in post-transcriptional regulation via the degradation or translational inhibition of their target genes. MicroRNA-150 (miR-150) plays a vital role in regulating the development of B and T lymphocytes. Although the ...


Cell and gene therapy for severe heart failure patients: The time and place for Pim-1 kinase

29-Aug-2013 | Sailay Siddiqi; Mark A Sussman, Expert Review of Cardiovascular Therapy, 2013

Regenerative therapy in severe heart failure patients presents a challenging set of circumstances including a damaged myocardial environment that accelerates senescence in myocytes and cardiac progenitor cells. Failing myocardium suffers from deterioration of contractile function coupled with ...


Myocardial structure, function and ischaemic tolerance in a rodent model of obesity with insulin resistance

23-Aug-2013 | I. Wensley, K. Salaveria, A. C. Bulmer, D. G. Donner, E. F. du Toit, Experimental Physiology, 2013

New findings • What is the central question of this study? Does obesity with insulin resistance decrease left ventricular pump function and/or myocardial tolerance to ischaemia in a rodent model of metabolic syndrome, and what mechanisms are involved in these changes? • What is the main ...


Does Health Related Quality of Life Predict Hospitalization or Mortality in Patients with Atrial Fibrillation?

22-Aug-2013 | ELEANOR SCHRON, ERIKA FRIEDMANN, SUE A. THOMAS, Journal of Cardiovascular Electrophysiology, 2013

Abstract Background Poor health related quality of life (QOL) is related to morbidity and mortality in coronary heart disease and ventricular arrhythmias as well as to mortality in patients with heart failure(HF) and atrial fibrillation(AF). This study examined the contributions of QOL to ...


The Registry Evaluating Functional Outcomes of Resynchronization Management (REFORM): Quality of Life and Psychological Functioning in Patients Receiving Cardiac Resynchronization Therapy


Abstract Background Cardiac resynchronization therapy (CRT) is a treatment for heart failure (HF) that improves cardiac, functional, and quality of life (QoL) outcomes. The present study was designed to examine the effect of the addition of CRT (CRTD) to the implantable cardioverter ...


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