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521 Newest Publications about the topic glucose metabolism

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Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia

14-Jun-2018 | Tom S. Chan; Shamir Cassim; Valérie-Ann Raymond; Sven Gottschalk; Grégory Merlen; Claudia Zwingmann; Pascal Lapierre ..., PLoS ONE, 2018

by Tom S. Chan, Shamir Cassim, Valérie-Ann Raymond, Sven Gottschalk, Grégory Merlen, Claudia Zwingmann, Pascal Lapierre, Peter Darby, Cyril David Mazer, Marc Bilodeau The liver is a highly vascularized organ receiving a dual input of oxygenated blood from the hepatic artery and portal vein. The ...

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Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents metabolic dysfunction and Alzheimer’s disease-related memory loss in senescence-accelerated prone 8 (SAMP8) mice fed a high-fat diet

01-Jun-2018 | Yutaro Kobayashi; Hiroyuki Inagawa; Chie Kohchi; Kimiko Kazumura; Hiroshi Tsuchiya; Toshiyuki Miwa; Katsuichiro Okaz ..., PLoS ONE, 2018

by Yutaro Kobayashi, Hiroyuki Inagawa, Chie Kohchi, Kimiko Kazumura, Hiroshi Tsuchiya, Toshiyuki Miwa, Katsuichiro Okazaki, Gen-Ichiro Soma The pathogenesis of Alzheimer’s disease (AD) remains unclear, but an imbalance between the production and clearance of amyloid-β (Aβ) peptides is known to ...

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A stimulating therapy for diabetes

25-May-2018 | Stella Hurtley; Mattia Maroso, Science , 2018

Diabetes In type 2 diabetes, insulin resistance leads to elevated blood glucose and increased risk of cardiovascular disorders. The brain participates in glucose metabolism, but whether and how modulation of brain activity affects systemic blood concentrations of glucose is poorly understood. In

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Targeting metabolism to treat psoriasis

07-May-2018 | Paul Hiebert; Sabine Werner, Nature Medicine, 2018

Targeting metabolism to treat psoriasis Targeting metabolism to treat psoriasis, Published online: 07 May 2018; doi:10.1038/s41591-018-0027-5 A crucial role for glucose metabolism has been identified in wound repair and in the pathogenesis of chronic inflammatory skin diseases, indicating that ...

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Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway

30-Apr-2018 | Shaojia Wang; Jiajia Li; Jie Xie; Fei Liu; Yachen Duan; Yong Wu; Shenglin Huang; Xianghuo He; Ziliang Wang; Xiaohua Wu, Oncogene, 2018

Although PD-L1 has been shown to play a well-characterized role in inhibiting antitumor immunity via engagement of its receptor PD-1 in T lymphocytes, little is known about the tumor cell-intrinsic function of PD-L1 and its association with prognosis. Here, we investigate this issue and dissect ...

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Changes in cerebral metabolic activity in men undergoing androgen deprivation therapy for non-metastatic prostate cancer

27-Apr-2018 | M. M. Cherrier; D. J. Cross; C. S. Higano; S. Minoshima, Prostate Cancer and Prostatic Diseases, 2018

Androgen deprivation therapy (ADT) is a common treatment option for men with biochemical relapse from prostate cancer. ADT is associated with changes in mood, cognition, and quality of life, and most recently with increased risk for Alzheimer’s disease (AD). This study examined changes in brain ...

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microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer

12-Mar-2018 | Sinae Kim; Eunji Lee; Jaeyun Jung; Jong Won Lee; Hee Jung Kim; Jisun Kim; Hyun ju Yoo; Hee Jin Lee; Sun Young Chae; ..., Oncogene, 2018

MicroRNA is an endogenous, small RNA controlling multiple target genes and playing roles in various biological processes including tumorigenesis. Here, we addressed the function of miR-155 using LC-MS/MS-based metabolic profiling of miR-155 deficient breast cancer cells. Our results revealed the ...

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Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis

09-Mar-2018 | Virginie-Anne Chouinard; David C. Henderson; Chiara Dalla Man; Linda Valeri; Brianna E. Gray; Kyle P. Ryan; Aaron M. ..., Molecular Psychiatry, 2018

Patients with psychotic disorders are at high risk for type 2 diabetes mellitus, and there is increasing evidence that patients display glucose metabolism abnormalities before significant antipsychotic medication exposure. In the present study, we examined insulin action by quantifying insulin ...

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Viruses, Vol. 10, Pages 114: Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1

07-Mar-2018 | Kavanagh Williamson, Maia ; Coombes, Naomi ; Juszczak, Florian ; Athanasopoulos, Marios ; Khan, Mariam B.; Eykyn, Th ..., Viruses, 2018

Viruses, Vol. 10, Pages 114: Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1 Viruses doi: 10.3390/v10030114 Authors: Maia Kavanagh Williamson Naomi Coombes Florian Juszczak Marios Athanasopoulos Mariam ...

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Mitochondrial inefficiency in infants born to overweight African-American mothers

03-Mar-2018 | Manjusha Abraham; Christina A. Collins; Scott Flewelling; Maraya Camazine; Alison Cahill; W. Todd Cade; Jennifer G. ..., International Journal of Obesity, 2018

Currently 20–35% of pregnant women are obese, posing a major health risk for mother and fetus. It is postulated that an abnormal maternal-fetal nutritional environment leads to adverse metabolic programming, resulting in altered substrate metabolism in the offspring and predisposing to risks of ...

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