My watch list
my.bionity.com  
Login  

1,270 Newest Publications about the topic dna replication

rss

You can refine your search further. Select from the filter options on the left to narrow down your results.

An archaeal primase functions as a nanoscale caliper to define primer length [Biochemistry]

26-Jun-2018 | Jiangyu Yan; Sandro Holzer; Luca Pellegrini; Stephen D. Bell, Proceedings of the National Academy of Sciences current issue, 2018

The first phosphodiester linkage made during DNA replication is in the context of a short RNA primer synthesized by the dedicated RNA polymerase, primase. Primase, after synthesizing a defined short oligoribonucleotide, then transfers this primer to a DNA polymerase for extension. The mechanisms ...

more

Conformational control and DNA-binding mechanism of the metazoan origin recognition complex [Biochemistry]

26-Jun-2018 | Franziska Bleichert; Alexander Leitner; Ruedi Aebersold; Michael R. Botchan; James M. Berger, Proceedings of the National Academy of Sciences current issue, 2018

The onset of chromosomal DNA replication relies on dedicated initiator proteins to chaperone ring-shaped helicases onto DNA. In most eukaryotes, initiators are multisubunit protein complexes that require ATP to bind DNA and to aid helicase recruitment and loading. Although structural studies have ...

more

Viruses, Vol. 10, Pages 321: The HPV E2 Transcriptional Transactivation Protein Stimulates Cellular DNA Polymerase Epsilon

12-Jun-2018 | Chojnacki, Michaelle ; Melendy, Thomas, Viruses, 2018

Viruses, Vol. 10, Pages 321: The HPV E2 Transcriptional Transactivation Protein Stimulates Cellular DNA Polymerase Epsilon Viruses doi: 10.3390/v10060321 Authors: Michaelle Chojnacki Thomas Melendy The papillomavirus (PV) protein E2 is one of only two proteins required for viral ...

more

Viruses, Vol. 10, Pages 313: The Odd “RB” Phage—Identification of Arabinosylation as a New Epigenetic Modification of DNA in T4-Like Phage RB69

08-Jun-2018 | Thomas, Julie A.; Orwenyo, Jared ; Wang, Lai-Xi ; Black, Lindsay W., Viruses, 2018

Viruses, Vol. 10, Pages 313: The Odd “RB” Phage—Identification of Arabinosylation as a New Epigenetic Modification of DNA in T4-Like Phage RB69 Viruses doi: 10.3390/v10060313 Authors: Julie A. Thomas Jared Orwenyo Lai-Xi Wang Lindsay W. Black In bacteriophages related to T4, ...

more

CAGE-seq analysis of Epstein-Barr virus lytic gene transcription: 3 kinetic classes from 2 mechanisms

04-Jun-2018 | Reza Djavadian; Mitchell Hayes; Eric Johannsen, PLoS Pathogens, 2018

by Reza Djavadian, Mitchell Hayes, Eric Johannsen Epstein-Barr virus (EBV) lytic replication proceeds through an ordered cascade of gene expression that integrates lytic DNA amplification and late gene transcription. We and others previously demonstrated that 6 EBV proteins that have orthologs ...

more

Nucleus Assembly and Import in Xenopus laevis Egg Extract

01-Jun-2018 | Chen, P., Levy, D. L., CSH Protocols, 2018

Xenopus egg extract represents a powerful cell-free biochemical tool for studying organelle assembly and function. Large quantities of cytoplasm can be isolated, and biochemical manipulation of extract composition and cell cycle state is relatively straightforward. In this protocol, we describe ...

more

Assembly of Spindles and Asters in Xenopus Egg Extracts

01-Jun-2018 | Field, C. M., Mitchison, T. J., CSH Protocols, 2018

Here, we provide methods for assembly of mitotic spindles and interphase asters in Xenopus laevis egg extract, and compare them to spindles and asters in the egg and zygote. Classic "cycled" spindles are made by adding sperm nuclei to metaphase-arrested cytostatic factor (CSF) extract and ...

more

Allele-specific control of replication timing and genome organization during development [RESEARCH]

01-Jun-2018 | Rivera-Mulia, J. C., Dimond, A., Vera, D., Trevilla-Garcia, C., Sasaki, T., Zimmerman, J., Dupont, C., Gribnau, J., ..., Genome Research, 2018

DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional activity and 3D genome organization. Here, we derived distinct cell types from F1 hybrid musculus x ...

more

Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling [Research Papers]

01-Jun-2018 | Michael Charles Lanz; Susannah Oberly; Ethan James Sanford; Sushma Sharma; Andrei Chabes; Marcus Bustamante Smolka, Genes & Development, 2018

The Mec1/ATR kinase coordinates multiple cellular responses to replication stress. In addition to its canonical role in activating the checkpoint kinase Rad53, Mec1 also plays checkpoint-independent roles in genome maintenance that are not well understood. Here we used a combined ...

more

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe

31-May-2018 | Takahisa Maki; Naoto Ogura; James E. Haber; Hiroshi Iwasaki; Geneviève Thon, PLoS Genetics, 2018

by Takahisa Maki, Naoto Ogura, James E. Haber, Hiroshi Iwasaki, Geneviève Thon Mating-type switching in Schizosaccharomyces pombe entails programmed gene conversion events regulated by DNA replication, heterochromatin, and the HP1-like chromodomain protein Swi6. The whole mechanism remains to ...

more

Page 1 From 127
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE