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1,582 Newest Publications about the topic dna repair

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Cloning and characterization of the promoter of baboonXRCC1, a gene involved in DNA strand-break repair

19-Jul-2007 | Zi-Qiang Zhou, Christi A. Walter, Somatic Cell and Molecular Genetics, 2007

The DNA repair geneXRCC1 was the first cloned human DNA repair gene involved in resistance to ionizing radiation. Previous studies have shown that rodent and baboon homologs ofXRCC1 are expressed in all tested tissues with significantly higher levels in testis. Furthermore, expression of ...

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Rare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity

18-Jul-2007 | E. A. Price, S. L. Bourne, R. Radbourne, P. A. Lawton, J. Lamerdin, L. H. Thompson, J. E. Arrand, Somatic Cell and Molecular Genetics, 2007

DNA repair defects might contribute both to cancer progression and to the extreme reactions to radiotherapy observed in ≈5% of patients. Polymorphic microsatellites in three DNA repair genes, XRCC1, XRCC3 and XRCC5, were analyzed for possible linkage to cancer status or clinical radiosensitivity. ...

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