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256 Newest Publications about the topic colitis ulcerosa

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Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats

14-Jun-2018 | Hadir M. Maher; Nourah Z. Alzoman; Shereen M. Shehata; Norah O. Abanmy, PLoS ONE, 2018

by Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Norah O. Abanmy Dasatinib (DAS) is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia and in the management of ulcerative colitis (UC). Since some nutraceuticals (e.g. curcumin, olive oil, and cocoa ...

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The role of diet in the aetiopathogenesis of inflammatory bowel disease

22-May-2018 | Hamed Khalili; Simon S. M. Chan; Paul Lochhead; Ashwin N. Ananthakrishnan; Andrew R. Hart; Andrew T. Chan, Nature Clinical Practice Gastroenterology & Hepatology, 2018

Crohn’s disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. Although the aetiopathogenesis of IBD is largely unknown, it is widely thought that diet has a crucial role in the development and progression of IBD. Indeed, ...

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Metabolic control of T cell immune response through glycans in inflammatory bowel disease [Immunology and Inflammation]

15-May-2018 | Ana M. Dias; Alexandra Correia; Márcia S. Pereira; Catarina R. Almeida; Inês Alves; Vanda Pinto; Telmo A. Catarino; ..., Proceedings of the National Academy of Sciences current issue, 2018

Our findings demonstrate that metabolic supplementation of mucosal T cells, isolated from patients with active ulcerative colitis (UC), with N -acetylglucosamine (GlcNAc) leads to the enhancement of branched N-glycosylation on the T cell receptor, which was associated with the control of T cell ...

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Human intestinal pro-inflammatory CD11chighCCR2+CX3CR1+ macrophages, but not their tolerogenic CD11c−CCR2−CX3CR1− counterparts, are expanded in inflammatory bowel disease

09-May-2018 | D. Bernardo; A. C. Marin; S. Fernández-Tomé; A. Montalban-Arques; A. Carrasco; E. Tristán; L. Ortega- ..., Mucosal Immunology, 2018

Although macrophages (Mϕ) maintain intestinal immune homoeostasis, there is not much available information about their subset composition, phenotype and function in the human setting. Human intestinal Mϕ (CD45+HLA-DR+CD14+CD64+) can be divided into subsets based on the expression of CD11c, CCR2 ...

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It is high time to examine the psyche while treating IBD

10-Apr-2018 | Antonina Mikocka-Walus; Jane M. Andrews, Nature Clinical Practice Gastroenterology & Hepatology, 2018

It is high time to examine the psyche while treating IBD It is high time to examine the psyche while treating IBD, Published online: 10 April 2018; doi:10.1038/s41575-018-0004-y In a prospective study of adults with Crohn’s disease or ulcerative colitis, Gracie and colleagues have found evidence ...

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Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort

28-Mar-2018 | Kelly A. Shaw; David J. Cutler; David Okou; Anne Dodd; Bruce J. Aronow; Yael Haberman; Christine Stevens; Thomas D. ..., Genes and Immunity, 2018

In the United States, approximately 5% of individuals with inflammatory bowel disease (IBD) are younger than 20 years old. Studies of pediatric cohorts can provide unique insights into genetic architecture of IBD, which includes Crohn’s disease (CD) and ulcerative colitis (UC). Large genome-wide ...

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Risk of infantile hemangiomas in the offspring of women with autoimmune disease and the pathogenic implications of these lesions

17-Jan-2018 | Chelsey J. F. Smith, Kenneth L. Jones, Diana L. Johnson, Gretchen Bandoli, Loan K. Robinson, Arthur Kavanaugh, Chris ..., American Journal of Medical Genetics Part A, 2018

The purpose of this study was to analyze the risk of maternal autoimmune disease or associated treatments on infantile hemangiomas (IHs), a common benign vascular tumor in infants, and to better understand how maternal chronic inflammation may play a factor in the pathogenesis of these lesions. ...

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Risk of infantile hemangiomas in the offspring of women with autoimmune disease and the pathogenic implications of these lesions

17-Jan-2018 | Chelsey J. F. Smith, Kenneth L. Jones, Diana L. Johnson, Gretchen Bandoli, Loan K. Robinson, Arthur Kavanaugh, Chris ..., American Journal of Medical Genetics Part A, 2018

The purpose of this study was to analyze the risk of maternal autoimmune disease or associated treatments on infantile hemangiomas (IHs), a common benign vascular tumor in infants, and to better understand how maternal chronic inflammation may play a factor in the pathogenesis of these lesions. ...

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Human Intestinal Dendritic Cells in Inflammatory Bowel Diseases

16-Jan-2018 | David Bernardo, María Chaparro, Javier P Gisbert, Molecular Nutrition & Food Research, 2018

Abstract Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a serious, costly and persistent health problem with an estimated prevalence in Western countries around 0.5% of the general population; its socioeconomic impact is comparable with that for chronic ...

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Alternative Foaming Agents for Topical Treatment of Ulcerative Colitis

03-Jan-2018 | Martin Asama, Alex Hall, Yijun Qi, Branden Moreau, Heidi Walthier, Matthew Schaschwary, Blaine Bristow, Qun Wang, Journal of Biomedical Materials Research Part A, 2018

Abstract Approximately 907,000 Americans currently suffer from ulcerative colitis, a condition characterized by inflammation of the large intestine or rectum. Treatment of this disease often includes anti‐inflammatory medication or immunosuppressants. Here foams are an attractive delivery ...

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