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73 Newest Publications about the topic cell culture media

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Viruses, Vol. 10, Pages 126: Development and Testing of a Method for Validating Chemical Inactivation of Ebola Virus

13-Mar-2018 | Alfson, Kendra J.; Griffiths, Anthony, Viruses, 2018

Viruses, Vol. 10, Pages 126: Development and Testing of a Method for Validating Chemical Inactivation of Ebola Virus Viruses doi: 10.3390/v10030126 Authors: Kendra Alfson Anthony Griffiths Complete inactivation of infectious Ebola virus (EBOV) is required before a sample may be ...

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Investigation of the Free Heavy Chain Homodimers of a Monoclonal Antibody

17-Jan-2018 | Hyo (Helen) Chung, Lynette Buck, Kristi Daris, Brent Welborn, Quanzhou Luo, Jette Wypych, Biotechnology Progress, 2018

Abstract Monoclonal antibodies (mAbs) are composed of two heavy chain (HC) and two light chain (LC) polypeptides. The proper folding and assembly of HC and LC is critical for antibody production. Current dogma indicates that the free HCs are retained in the endoplasmic reticulum (ER) unless ...

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Inhibition of Apoptosis Using Exosomes in Chinese Hamster Ovary Cell Culture

16-Jan-2018 | Seora Han, Won Jong Rhee, Biotechnology and Bioengineering, 2018

Abstract Animal cell culture technology for therapeutic protein production has shown significant improvement over the last few decades. Chinese hamster ovary (CHO) cells have been widely adapted for the production of biopharmaceutical drugs. In the biopharmaceutical industry, it is crucial to ...

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Highly porous scaffolds of PEDOT:PSS for bone tissue engineering

14-Oct-2017 | Author(s): Anne Géraldine Guex, Jennifer L. Puetzer, Astrid Armgarth, Elena Littmann, Eleni Stavrinidou, E ..., Acta Biomaterialia, 2017

Publication date: 15 October 2017 Source:Acta Biomaterialia, Volume 62 Author(s): Anne Géraldine Guex, Jennifer L. Puetzer, Astrid Armgarth, Elena Littmann, Eleni Stavrinidou, Emmanuel P. Giannelis, George G. Malliaras, Molly M. Stevens Conjugated polymers have been ...

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Myricetin solid lipid nanoparticles: Stability assurance from system preparation to site of action

24-Sep-2017 | Author(s): Dina M. Gaber, Noha Nafee, Osama Y. Abdallah, European Journal of Pharmaceutical Science, 2017

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Dina M. Gaber, Noha Nafee, Osama Y. Abdallah Myricetin - a natural flavonoid - has attracted a great interest due to its antioxidant and free-radical scavenging potential. ...

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Myricetin solid lipid nanoparticles: Stability assurance from system preparation to site of action

24-Sep-2017 | Author(s): Dina M. Gaber, Noha Nafee, Osama Y. Abdallah, European Journal of Pharmaceutical Science, 2017

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Dina M. Gaber, Noha Nafee, Osama Y. Abdallah Myricetin - a natural flavonoid - has attracted a great interest due to its antioxidant and free-radical scavenging potential. ...

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Parametric studies on droplet generation reproducibility for applications with biological relevant fluids

29-Aug-2017 | Stefan Wiedemeier, Marko Eichler, Robert Römer, Andreas Grodrian, Karen Lemke, Krees Nagel, Claus‐Peter Klages, Gunt ..., Engineering in Life Sciences, 2017

Although the great potential of droplet based microfluidic technologies for routine applications in industry and academia has been successfully demonstrated over the past years, its inherent potential is not fully exploited till now. Especially regarding to the droplet generation reproducibility ...

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A ‘degradable’ poly(vinyl alcohol) iron oxide nanoparticle hydrogel

22-May-2017 | Author(s): Dawn Bannerman, Xinyi Li, Wankei Wan, Acta Biomaterialia, 2017

Publication date: Available online 10 May 2017 Source:Acta Biomaterialia Author(s): Dawn Bannerman, Xinyi Li, Wankei Wan Polymeric materials that contain magnetic nanoparticles are extremely useful in many applications including as multifunctional drug carriers, imaging contrast ...

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Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging established fed‐batch media

03-Apr-2017 | Henry Lin, Robert Woodrow Leighty, Scott Godfrey, Samantha Boran Wang, Biotechnology Progress, 2017

Abstract Perfusion medium was successfully developed based on our fed‐batch platform basal and feed media. A systematic development approach was undertaken by first optimizing the ratios of fed‐batch basal and feed media followed by targeted removal of unnecessary and redundant components. ...

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A novel sugar analog enhances sialic acid production and biotherapeutic sialylation in CHO cells

15-Mar-2017 | Bojiao Yin, Qiong Wang, Cheng‐Yu Chung, Rahul Bhattacharya, Xiaozhi Ren, Juechun Tang, Kevin J. Yarema, Michael J. B ..., Biotechnology and Bioengineering, 2017

Abstract A desirable feature of many therapeutic glycoprotein production processes is to maximize the final sialic acid content. In this study, the effect of applying a novel chemical analog of the sialic acid precursor N‐acetylmannosamine (ManNAc) on the sialic acid content of cellular ...

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