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3,876 Newest Publications of Expert Reviews

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Devices for stem cell isolation and delivery: current need for drug discovery and cell therapy

25-Dec-2014 | Martin Reinhardt; Augustinus Bader; Shibashish Giri, Expert Review of Medical Devices, 2014

Isolation and purification of stem cells and their delivery into diseased or aged tissues or organs need special devices for proper transplantation of stem cells in order to achieve high cell retention at transplant site for repair or regeneration of tissues and organs. The clinical and ...

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Is robotic arm stereotactic body radiation therapy ‘virtual high-dose rate brachytherapy’ for prostate cancer? an analysis of comparative effectiveness using published data

25-Dec-2014 | Nicholas George Zaorsky; Mark D Hurwitz; Adam P Dicker; Timothy N Showalter; Robert B Den, Expert Review of Medical Devices, 2014

High-dose rate brachytherapy (HDR-BT) monotherapy and robotic arm (i.e., CyberKnife) stereotactic body radiation therapy (SBRT) are emerging technologies that have become popular treatment options for prostate cancer. Proponents of both HDR-BT monotherapy and robotic arm SBRT claim that these ...

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NOS2 and CCL27: clinical implications for psoriasis and eczema diagnosis and management

25-Dec-2014 | Natalie Garzorz; Kilian Eyerich, Expert Review of Molecular Diagnostics, 2014

Chronic inflammatory skin diseases such as psoriasis and eczema are a major medical challenge. Development of highly specific therapies for both conditions is opposed by the lack of translation of basic knowledge into biomarkers for clinical use. Furthermore, to distinguish psoriasis from eczema ...

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Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future

24-Dec-2014 | Harald Hampel; Lon S Schneider; Ezio Giacobini; Miia Kivipelto; Shireen Sindi; Bruno Dubois; Karl Broich; Robert Nis ..., Expert Review of Neurotherapeutics, 2014

Worldwide multidisciplinary translational research has led to a growing knowledge of the genetics and molecular pathogenesis of Alzheimer’s disease (AD) indicating that pathophysiological brain alterations occur decades before clinical signs and symptoms of cognitive decline can be diagnosed. ...

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Serum pentosidine levels after 3 years of bisphosphonate treatment in post-menopausal osteoporotic women

23-Dec-2014 | Hiroyuki Hashidate; Mikio Kamimura; Shota Ikegami; Keijiro Mukaiyama; Shigeharu Uchiyama; Yukio Nakamura; Hiroyuki Kato, Expert Review of Cardiovascular Therapy, 2014

Abstract The present study measured changes in plasma pentosidine and bone turnover markers in elderly patients with osteoporosis treated using bisphosphonate. The relationship between pentosidine and bone turnover markers and bone mineral density (BMD) was investigated. This study consisted of ...

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Virus-driven autoimmunity and lymphoproliferation: the example of HCV infection

23-Dec-2014 | Anna Linda Zignego; Laura Gragnani; Alessia Piluso; Marco Sebastiani; Dilia Giuggioli; Poupak Fallahi; Alessandro An ..., Expert Review of Molecular Diagnostics, 2014

HCV chronic infection is characterized by possible development of both hepatic and extrahepatic manifestations. The infection by this both hepatotropic and lymphotropic virus is responsible for polyoligoclonal B-lymphocyte expansion, leading to several immune-mediated disorders. Mixed ...

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Hypovitaminosis D in type 2 diabetes: relation with features of the metabolic syndrome and glycemic control

23-Dec-2014 | Inka Miñambres; Jose Luis Sánchez-Quesada; Irene Vinagre; Joan Sánchez-Hernández; Eulalia Urgell; Alberto de Leiva; ..., Expert Review of Cardiovascular Therapy, 2014

Abstract Aim: To assess the association of hypovitaminosis D with clinical and biochemical characteristics of type 2 diabetic patients and to determine the effect of glycemic control optimization on 25-hydroxyvitamin D (25(OH)D) concentrations. Methods: Cross-sectional study of 63 patients with ...

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Expert Review of Clinical Immunology 10-year anniversary issue

23-Dec-2014 | Thomas G Forsthuber; Timothy RDJ Radstake, Expert Review of Molecular Diagnostics, 2014

Expert Review of Clinical Immunology, Volume 11, Issue 1, Page 1-3, January 2015.

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Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?

23-Dec-2014 | Matlock A Jeffries; Amr H Sawalha, Expert Review of Molecular Diagnostics, 2014

Autoimmune diseases are complex and enigmatic, and have presented particular challenges to researchers seeking to define their etiology and explain progression. Previous studies have implicated epigenetic influences in the development of autoimmunity. Epigenetics describes changes in gene ...

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Waist-to-height ratio is independently associated with chronic kidney disease in overweight type 2 diabetic patients

23-Dec-2014 | Kristina Blaslov; Tomislav Bulum; Lea Duvnjak, Expert Review of Cardiovascular Therapy, 2014

Abstract Objective: Chronic kidney disease (CKD) is one of the most serious complications in obesity-induced type 2 diabetes mellitus (T2DM). Body mass index (BMI), waist-to-hip ratio (WHR), waist circumference (WC) and waist-to-height ratio (WHtR) are recognised as sensitive obesity measures. We ...

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